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BDBM50003374 2,6-Dimethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethoxy]-quinoline::CHEMBL130455

SMILES: Cc1ccc2nc(C)cc(OCc3ccc(cc3)-c3ccccc3-c3nnn[nH]3)c2c1

InChI Key: InChIKey=DJHYAKMFKDRSGV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003374   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Type-1 angiotensin II receptor


(Cavia porcellus)
BDBM50003374
PNG
(2,6-Dimethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-y...)
Show SMILES Cc1ccc2nc(C)cc(OCc3ccc(cc3)-c3ccccc3-c3nnn[nH]3)c2c1
Show InChI InChI=1S/C25H21N5O/c1-16-7-12-23-22(13-16)24(14-17(2)26-23)31-15-18-8-10-19(11-9-18)20-5-3-4-6-21(20)25-27-29-30-28-25/h3-14H,15H2,1-2H3,(H,27,28,29,30)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 470n/an/an/an/an/an/a



ICI Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparation


J Med Chem 35: 4027-38 (1992)


Article DOI: 10.1021/jm00100a007
BindingDB Entry DOI: 10.7270/Q2G44P8Q
More data for this
Ligand-Target Pair