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BDBM50008757 5,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione::CHEMBL282003

SMILES: Clc1cc(Cl)c2[nH]c(=O)c(=O)[nH]c2c1

InChI Key: InChIKey=DBSHFABBWSZJLZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50008757   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ionotropic glutamate receptor NMDA 1/2D


(RAT)
BDBM50008757
PNG
(5,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione | C...)
Show SMILES Clc1cc(Cl)c2[nH]c(=O)c(=O)[nH]c2c1
Show InChI InChI=1S/C8H4Cl2N2O2/c9-3-1-4(10)6-5(2-3)11-7(13)8(14)12-6/h1-2H,(H,11,13)(H,12,14)
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PC sid
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Article
PubMed
n/an/a 280n/an/an/an/an/an/a



CoCensys Inc

Curated by ChEMBL


Assay Description
Inhibition of [3H]- DCKA binding to NMDA receptor of rat brain membranes


J Med Chem 39: 3248-55 (1996)


Article DOI: 10.1021/jm960214k
BindingDB Entry DOI: 10.7270/Q2QC02KC
More data for this
Ligand-Target Pair