BDBM50049189 3-[4-(2-Ethyl-57-dimethyl-imidazo[45-b]pyridin-3-ylmethyl)-phenyl]-5-isobutyl-thiophene-2-sulfonic acid butyloxycarbonylamide(L-162313)::CHEMBL288174::L-162313::butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl)phenyl)-5-isobutylthiophen-2-ylsulfonylcarbamate

SMILES: CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1

InChI Key: InChIKey=RINPELQWLUGERM-UHFFFAOYSA-N

Data: 11 KI  7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50049189   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-2 angiotensin II receptor (Rat)	BDBM50049189 (butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Human)	BDBM50049189 (butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Human)	BDBM50049189 (butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Human)	BDBM50049189 (butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Human)	BDBM50049189 (butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Human)	BDBM50049189 (butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Human)	BDBM50049189 (butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Human)	BDBM50049189 (butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b...) Show SMILES Show InChI	GoogleScholar	UniChem		1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A (Rat)	BDBM50049189 (butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b...) Show SMILES Show InChI	GoogleScholar	UniChem		1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Human)	BDBM50049189 (butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Pig)	BDBM50049189 (butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Human)	BDBM50049189 (butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b...) Show SMILES Show InChI	GoogleScholar	UniChem		2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Human)	BDBM50049189 (butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b...) Show SMILES Show InChI	GoogleScholar	UniChem		2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Human)	BDBM50049189 (butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b...) Show SMILES Show InChI	GoogleScholar	UniChem		2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Pig)	BDBM50049189 (butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b...) Show SMILES Show InChI	GoogleScholar	UniChem		2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Human)	BDBM50049189 (butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b...) Show SMILES Show InChI	GoogleScholar	UniChem		3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A (Rat)	BDBM50049189 (butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b...) Show SMILES Show InChI	GoogleScholar	UniChem		3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A (Rat)	BDBM50049189 (butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b...) Show SMILES Show InChI	GoogleScholar	UniChem		3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair