BDBM50067921 4-((E)-2-{[2',4'-Dimethyl-3'-(2-methyl-quinolin-8-yloxymethyl)-biphenyl-2-ylmethyl]-carbamoyl}-vinyl)-N-methyl-benzamide::CHEMBL140383

SMILES CNC(=O)c1ccc(\C=C\C(=O)NCc2ccccc2-c2ccc(C)c(COc3cccc4ccc(C)nc34)c2C)cc1

InChI Key InChIKey=AFUNWCBOHPULNY-LTGZKZEYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50067921   

TargetB2 bradykinin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067921(4-((E)-2-{[2',4'-Dimethyl-3'-(2-methyl-quinolin-8-...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of the specific binding of [3H]BK to human recombinant Bradykinin receptor B2 expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Cavia porcellus)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067921(4-((E)-2-{[2',4'-Dimethyl-3'-(2-methyl-quinolin-8-...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of the specific binding of [3H]BK to Bradykinin receptor B2 in guinea pig ileum membrane preparationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed