BDBM50081908 5-(3-Methoxy-benzyl)-pyrimidine-2,4-diamine::CHEMBL18967

SMILES: COc1cccc(Cc2cnc(N)nc2N)c1

InChI Key: InChIKey=VJSZGADWCZOKOK-UHFFFAOYSA-N

Data: 17 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50081908   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrofolate reductase (Escherichia coli)	BDBM50081908 (5-(3-Methoxy-benzyl)-pyrimidine-2,4-diamine | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Human)	BDBM50081908 (5-(3-Methoxy-benzyl)-pyrimidine-2,4-diamine | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Escherichia coli)	BDBM50081908 (5-(3-Methoxy-benzyl)-pyrimidine-2,4-diamine | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Escherichia coli)	BDBM50081908 (5-(3-Methoxy-benzyl)-pyrimidine-2,4-diamine | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Escherichia coli)	BDBM50081908 (5-(3-Methoxy-benzyl)-pyrimidine-2,4-diamine | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Dihydrofolate reductase (Escherichia coli)	BDBM50081908 (5-(3-Methoxy-benzyl)-pyrimidine-2,4-diamine | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Salmonella typhi)	BDBM50081908 (5-(3-Methoxy-benzyl)-pyrimidine-2,4-diamine | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Human)	BDBM50081908 (5-(3-Methoxy-benzyl)-pyrimidine-2,4-diamine | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Human)	BDBM50081908 (5-(3-Methoxy-benzyl)-pyrimidine-2,4-diamine | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Lactobacillus casei)	BDBM50081908 (5-(3-Methoxy-benzyl)-pyrimidine-2,4-diamine | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Lactobacillus casei)	BDBM50081908 (5-(3-Methoxy-benzyl)-pyrimidine-2,4-diamine | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Human)	BDBM50081908 (5-(3-Methoxy-benzyl)-pyrimidine-2,4-diamine | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Bovine)	BDBM50081908 (5-(3-Methoxy-benzyl)-pyrimidine-2,4-diamine | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		2.46E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
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					More data for this Ligand-Target Pair
Dihydrofolate reductase (Bovine)	BDBM50081908 (5-(3-Methoxy-benzyl)-pyrimidine-2,4-diamine | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		2.46E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
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Dihydrofolate reductase (Bovine)	BDBM50081908 (5-(3-Methoxy-benzyl)-pyrimidine-2,4-diamine | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		9.55E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Chicken)	BDBM50081908 (5-(3-Methoxy-benzyl)-pyrimidine-2,4-diamine | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		3.55E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Dihydrofolate reductase (Chicken)	BDBM50081908 (5-(3-Methoxy-benzyl)-pyrimidine-2,4-diamine | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		3.55E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Chicken)	BDBM50081908 (5-(3-Methoxy-benzyl)-pyrimidine-2,4-diamine | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		3.55E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
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					More data for this Ligand-Target Pair