BindingDB logo
myBDB logout

BDBM50102113 (2R,4R)-4-amino-1-(pyridin-2-ylmethyl)pyrrolidine-2,4-dicarboxylic acid trihydrochloride::CHEMBL543811

SMILES: N[C@@]1(C[C@@H](N(Cc2ccccn2)C1)C(O)=O)C(O)=O

InChI Key: InChIKey=DBFCNSLCXUQJOU-BXKDBHETSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50102113   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM50102113
PNG
((2R,4R)-4-amino-1-(pyridin-2-ylmethyl)pyrrolidine-...)
Show SMILES N[C@@]1(C[C@@H](N(Cc2ccccn2)C1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H15N3O4/c13-12(11(18)19)5-9(10(16)17)15(7-12)6-8-3-1-2-4-14-8/h1-4,9H,5-7,13H2,(H,16,17)(H,18,19)/t9-,12-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 3.70E+4n/an/an/an/a



Georgetown University Medical Center

Curated by ChEMBL


Assay Description
Effective concentration required for agonistic activity at Metabotropic glutamate receptor 2


Bioorg Med Chem Lett 11: 1919-24 (2001)


Article DOI: 10.1016/s0960-894x(01)00329-8
BindingDB Entry DOI: 10.7270/Q2SQ90XH
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM50102113
PNG
((2R,4R)-4-amino-1-(pyridin-2-ylmethyl)pyrrolidine-...)
Show SMILES N[C@@]1(C[C@@H](N(Cc2ccccn2)C1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H15N3O4/c13-12(11(18)19)5-9(10(16)17)15(7-12)6-8-3-1-2-4-14-8/h1-4,9H,5-7,13H2,(H,16,17)(H,18,19)/t9-,12-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 3.70E+4n/an/an/an/a



Georgetown University Medical Center

Curated by ChEMBL


Assay Description
Effective concentration required for agonistic activity at Metabotropic glutamate receptor 3


Bioorg Med Chem Lett 11: 1919-24 (2001)


Article DOI: 10.1016/s0960-894x(01)00329-8
BindingDB Entry DOI: 10.7270/Q2SQ90XH
More data for this
Ligand-Target Pair