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BDBM50115046 CHEMBL50591::Cyclohexanecarboxylic acid [(6aR,10aS)-4-(4,5,7,8,10,10a-hexahydro-6aH-pyrido[4,3-b]pyrrolo[3,2,1-hi]indol-9-yl)-butyl]-amide

SMILES: O=C(NCCCCN1CC[C@@H]2[C@H](C1)c1cccc3CCN2c13)C1CCCCC1

InChI Key: InChIKey=AOIYRGJEOWHRNF-FGZHOGPDSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50115046   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50115046
PNG
(CHEMBL50591 | Cyclohexanecarboxylic acid [(6aR,10a...)
Show SMILES O=C(NCCCCN1CC[C@@H]2[C@H](C1)c1cccc3CCN2c13)C1CCCCC1
Show InChI InChI=1S/C24H35N3O/c28-24(19-7-2-1-3-8-19)25-13-4-5-14-26-15-12-22-21(17-26)20-10-6-9-18-11-16-27(22)23(18)20/h6,9-10,19,21-22H,1-5,7-8,11-17H2,(H,25,28)/t21-,22-/m1/s1
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UniProtKB/SwissProt
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.10E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
In vitro inhibition if C-C chemokine receptor type 3 (CCR3) using 150p M [125I]-labeled human eotaxin


Bioorg Med Chem Lett 12: 1785-9 (2002)


Article DOI: 10.1016/s0960-894x(02)00206-8
BindingDB Entry DOI: 10.7270/Q28W3CN8
More data for this
Ligand-Target Pair