BindingDB logo
myBDB logout

BDBM50129186 CHEMBL305391::N-(5-Amino-pentyl)-2-((S)-3-benzyl-ureido)-3-(1H-indol-3-yl)-propionamide

SMILES: NCCCCCNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)NCc1ccccc1

InChI Key: InChIKey=CWJHVSDNADCVQK-QFIPXVFZSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50129186   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 1


(Mus musculus)
BDBM50129186
PNG
(CHEMBL305391 | N-(5-Amino-pentyl)-2-((S)-3-benzyl-...)
Show SMILES NCCCCCNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)NCc1ccccc1
Show InChI InChI=1S/C24H31N5O2/c25-13-7-2-8-14-26-23(30)22(15-19-17-27-21-12-6-5-11-20(19)21)29-24(31)28-16-18-9-3-1-4-10-18/h1,3-6,9-12,17,22,27H,2,7-8,13-16,25H2,(H,26,30)(H2,28,29,31)/t22-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.48E+4n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Agonist activity on mouse melanocortin 1 receptor (mMC1R) stably expressed in HEK cells


Bioorg Med Chem Lett 13: 2079-82 (2003)


Article DOI: 10.1016/s0960-894x(03)00318-4
BindingDB Entry DOI: 10.7270/Q2JD4XBW
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50129186
PNG
(CHEMBL305391 | N-(5-Amino-pentyl)-2-((S)-3-benzyl-...)
Show SMILES NCCCCCNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)NCc1ccccc1
Show InChI InChI=1S/C24H31N5O2/c25-13-7-2-8-14-26-23(30)22(15-19-17-27-21-12-6-5-11-20(19)21)29-24(31)28-16-18-9-3-1-4-10-18/h1,3-6,9-12,17,22,27H,2,7-8,13-16,25H2,(H,26,30)(H2,28,29,31)/t22-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.00E+4n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Agonist activity on mouse melanocortin 5 receptor (mMC5R) stably expressed in HEL cells


Bioorg Med Chem Lett 13: 2079-82 (2003)


Article DOI: 10.1016/s0960-894x(03)00318-4
BindingDB Entry DOI: 10.7270/Q2JD4XBW
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50129186
PNG
(CHEMBL305391 | N-(5-Amino-pentyl)-2-((S)-3-benzyl-...)
Show SMILES NCCCCCNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)NCc1ccccc1
Show InChI InChI=1S/C24H31N5O2/c25-13-7-2-8-14-26-23(30)22(15-19-17-27-21-12-6-5-11-20(19)21)29-24(31)28-16-18-9-3-1-4-10-18/h1,3-6,9-12,17,22,27H,2,7-8,13-16,25H2,(H,26,30)(H2,28,29,31)/t22-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Agonist activity on mouse melanocortin 4 receptor (mMC4R) stably expressed in HEL cells


Bioorg Med Chem Lett 13: 2079-82 (2003)


Article DOI: 10.1016/s0960-894x(03)00318-4
BindingDB Entry DOI: 10.7270/Q2JD4XBW
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50129186
PNG
(CHEMBL305391 | N-(5-Amino-pentyl)-2-((S)-3-benzyl-...)
Show SMILES NCCCCCNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)NCc1ccccc1
Show InChI InChI=1S/C24H31N5O2/c25-13-7-2-8-14-26-23(30)22(15-19-17-27-21-12-6-5-11-20(19)21)29-24(31)28-16-18-9-3-1-4-10-18/h1,3-6,9-12,17,22,27H,2,7-8,13-16,25H2,(H,26,30)(H2,28,29,31)/t22-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Agonist activity on mouse Melanocortin 3 receptor (mMC3R) stably expressed in HEK cells


Bioorg Med Chem Lett 13: 2079-82 (2003)


Article DOI: 10.1016/s0960-894x(03)00318-4
BindingDB Entry DOI: 10.7270/Q2JD4XBW
More data for this
Ligand-Target Pair