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BDBM50169600 3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indole; hydrochloride::CHEMBL539327

SMILES: CN1CCC[C@@H]1Cc1c[nH]c2ccccc12

InChI Key: InChIKey=HCTCDEAMCNSARD-GFCCVEGCSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50169600   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (human))
BDBM50169600
PNG
(3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indole; ...)
Show SMILES CN1CCC[C@@H]1Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C14H18N2/c1-16-8-4-5-12(16)9-11-10-15-14-7-3-2-6-13(11)14/h2-3,6-7,10,12,15H,4-5,8-9H2,1H3/t12-/m1/s1
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PC cid
PC sid
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Similars

Article
PubMed
640n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against h5-HT6 receptor transiently expressed in HEK293 cells


Bioorg Med Chem Lett 15: 3510-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.092
BindingDB Entry DOI: 10.7270/Q20Z7411
More data for this
Ligand-Target Pair