BDBM50181914 2-(2-Fluoro-biphenyl-4-yl)-2-methyl-propionic acid::CHEMBL380853
SMILES CC(C)(C(O)=O)c1ccc(c(F)c1)-c1ccccc1
InChI Key InChIKey=UTJOTVGFUYHIRG-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50181914
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of COX2-mediated 2-arachidonoylglycerol oxygenation in LPS/IFN-gamma-stimulated mouse RAW264.7 cells assessed as 2-AG to PGE2-G/PGD2-G con...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of mouse COX2-mediated 2-arachidonoylglycerol oxygenation preincubated for 3 mins before 2-arachidonoylglycerol addition measured after 30...More data for this Ligand-Target Pair