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BDBM50199189 6-methyl-3-beta-D-ribofuranosyl(1H)pyrimidine-2,4-dione 5'-triphosphate::CHEMBL413841

SMILES: Cc1cc(=O)n([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)[nH]1

InChI Key: InChIKey=AROARRWARGPJJC-ZOQUXTDFSA-N

Data: 3 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50199189   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Pyrimidinergic receptor P2Y4


(Homo sapiens (Human))
BDBM50199189
PNG
(6-methyl-3-beta-D-ribofuranosyl(1H)pyrimidine-2,4-...)
Show SMILES Cc1cc(=O)n([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)[nH]1
Show InChI InChI=1S/C10H17N2O15P3/c1-4-2-6(13)12(10(16)11-4)9-8(15)7(14)5(25-9)3-24-29(20,21)27-30(22,23)26-28(17,18)19/h2,5,7-9,14-15H,3H2,1H3,(H,11,16)(H,20,21)(H,22,23)(H2,17,18,19)/t5-,7-,8-,9-/m1/s1
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KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y4 receptor expressed in 1321N1 cells assessed as IP accumulation by SPA


J Med Chem 49: 7076-87 (2006)


Article DOI: 10.1021/jm060848j
BindingDB Entry DOI: 10.7270/Q2SN09RW
More data for this
Ligand-Target Pair
Pyrimidinergic receptor P2Y6


(Homo sapiens (Human))
BDBM50199189
PNG
(6-methyl-3-beta-D-ribofuranosyl(1H)pyrimidine-2,4-...)
Show SMILES Cc1cc(=O)n([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)[nH]1
Show InChI InChI=1S/C10H17N2O15P3/c1-4-2-6(13)12(10(16)11-4)9-8(15)7(14)5(25-9)3-24-29(20,21)27-30(22,23)26-28(17,18)19/h2,5,7-9,14-15H,3H2,1H3,(H,11,16)(H,20,21)(H,22,23)(H2,17,18,19)/t5-,7-,8-,9-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y6 receptor expressed in 1321N1 cells assessed as IP accumulation by SPA


J Med Chem 49: 7076-87 (2006)


Article DOI: 10.1021/jm060848j
BindingDB Entry DOI: 10.7270/Q2SN09RW
More data for this
Ligand-Target Pair
Purinergic receptor P2Y2


(Homo sapiens (Human))
BDBM50199189
PNG
(6-methyl-3-beta-D-ribofuranosyl(1H)pyrimidine-2,4-...)
Show SMILES Cc1cc(=O)n([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)[nH]1
Show InChI InChI=1S/C10H17N2O15P3/c1-4-2-6(13)12(10(16)11-4)9-8(15)7(14)5(25-9)3-24-29(20,21)27-30(22,23)26-28(17,18)19/h2,5,7-9,14-15H,3H2,1H3,(H,11,16)(H,20,21)(H,22,23)(H2,17,18,19)/t5-,7-,8-,9-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y2 receptor expressed in 1321N1 cells assessed as IP accumulation by SPA


J Med Chem 49: 7076-87 (2006)


Article DOI: 10.1021/jm060848j
BindingDB Entry DOI: 10.7270/Q2SN09RW
More data for this
Ligand-Target Pair