BDBM50247069 2-(7-(benzyloxy)-1H-indol-3-yl)ethanamine::CHEMBL460302

SMILES NCCc1c[nH]c2c(OCc3ccccc3)cccc12

InChI Key InChIKey=JOYGWYISRWPUIM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50247069   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50247069(2-(7-(benzyloxy)-1H-indol-3-yl)ethanamine | CHEMBL...)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of aminopeptidase activity of human leukotriene A4 hydrolase assessed as para-nitroanilide release by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50247069(2-(7-(benzyloxy)-1H-indol-3-yl)ethanamine | CHEMBL...)
Affinity DataIC50:  2.17E+5nMAssay Description:Inhibition of epoxide hydrolase activity of human leukotriene A4 hydrolase assessed as LTB4 level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50247069(2-(7-(benzyloxy)-1H-indol-3-yl)ethanamine | CHEMBL...)
Affinity DataIC50:  8.93E+3nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50247069(2-(7-(benzyloxy)-1H-indol-3-yl)ethanamine | CHEMBL...)
Affinity DataIC50:  3.34E+3nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50247069(2-(7-(benzyloxy)-1H-indol-3-yl)ethanamine | CHEMBL...)
Affinity DataIC50:  5.25E+4nMAssay Description:Inhibition of human nonpancreatic secretory phospholipase A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed