BDBM50249090 3,3'-(5-fluoropyrimidine-2,4-diyl)bis(azanediyl)diphenol::CHEMBL515271

SMILES: Oc1cccc(Nc2ncc(F)c(Nc3cccc(O)c3)n2)c1

InChI Key: InChIKey=TVKGTSHBQZEFEE-UHFFFAOYSA-N

Data: 2 KI  2 IC50  10 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50249090   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Human)	BDBM50249090 (3,3'-(5-fluoropyrimidine-2,4-diyl)bis(azanediyl)di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50249090 (3,3'-(5-fluoropyrimidine-2,4-diyl)bis(azanediyl)di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50249090 (3,3'-(5-fluoropyrimidine-2,4-diyl)bis(azanediyl)di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50249090 (3,3'-(5-fluoropyrimidine-2,4-diyl)bis(azanediyl)di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50249090 (3,3'-(5-fluoropyrimidine-2,4-diyl)bis(azanediyl)di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50249090 (3,3'-(5-fluoropyrimidine-2,4-diyl)bis(azanediyl)di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.01E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50249090 (3,3'-(5-fluoropyrimidine-2,4-diyl)bis(azanediyl)di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	115	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50249090 (3,3'-(5-fluoropyrimidine-2,4-diyl)bis(azanediyl)di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	490	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50249090 (3,3'-(5-fluoropyrimidine-2,4-diyl)bis(azanediyl)di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	353	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50249090 (3,3'-(5-fluoropyrimidine-2,4-diyl)bis(azanediyl)di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	280	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50249090 (3,3'-(5-fluoropyrimidine-2,4-diyl)bis(azanediyl)di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50249090 (3,3'-(5-fluoropyrimidine-2,4-diyl)bis(azanediyl)di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50249090 (3,3'-(5-fluoropyrimidine-2,4-diyl)bis(azanediyl)di...) Show SMILES Show InChI	GoogleScholar	UniChem		96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50249090 (3,3'-(5-fluoropyrimidine-2,4-diyl)bis(azanediyl)di...) Show SMILES Show InChI	GoogleScholar	UniChem		96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair