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BDBM50297584 CHEMBL550614::N-(3-(3-aminophenylamino)quinoxalin-2-yl)-4-chlorobenzenesulfonamide

SMILES: Nc1cccc(Nc2nc3ccccc3nc2NS(=O)(=O)c2ccc(Cl)cc2)c1

InChI Key: InChIKey=BNDGOTGKFXPONZ-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297584   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dual specificity phosphatase Cdc25B


(Homo sapiens (Human))
BDBM50297584
PNG
(CHEMBL550614 | N-(3-(3-aminophenylamino)quinoxalin...)
Show SMILES Nc1cccc(Nc2nc3ccccc3nc2NS(=O)(=O)c2ccc(Cl)cc2)c1
Show InChI InChI=1S/C20H16ClN5O2S/c21-13-8-10-16(11-9-13)29(27,28)26-20-19(23-15-5-3-4-14(22)12-15)24-17-6-1-2-7-18(17)25-20/h1-12H,22H2,(H,23,24)(H,25,26)
PDB
MMDB

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CHEMBL
PC cid
PC sid
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Similars

Article
PubMed
n/an/a 1.11E+4n/an/an/an/an/an/a



Sejong University

Curated by ChEMBL


Assay Description
Inhibition of GST-fused Cdc25B


Bioorg Med Chem Lett 19: 4372-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.078
BindingDB Entry DOI: 10.7270/Q2D79BGK
More data for this
Ligand-Target Pair
phosphatase Cdc25


(Homo sapiens (Human))
BDBM50297584
PNG
(CHEMBL550614 | N-(3-(3-aminophenylamino)quinoxalin...)
Show SMILES Nc1cccc(Nc2nc3ccccc3nc2NS(=O)(=O)c2ccc(Cl)cc2)c1
Show InChI InChI=1S/C20H16ClN5O2S/c21-13-8-10-16(11-9-13)29(27,28)26-20-19(23-15-5-3-4-14(22)12-15)24-17-6-1-2-7-18(17)25-20/h1-12H,22H2,(H,23,24)(H,25,26)
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.30E+3n/an/an/an/an/an/a



Sejong University

Curated by ChEMBL


Assay Description
Inhibition of Cdc25A


Bioorg Med Chem Lett 19: 4372-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.078
BindingDB Entry DOI: 10.7270/Q2D79BGK
More data for this
Ligand-Target Pair