BDBM50317478 5-(azocan-1-yl)-7-benzyl-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine::CHEMBL1094771

SMILES: Nc1n[nH]c2nc(N3CCCCCCC3)c3CN(Cc4ccccc4)CCc3c12

InChI Key: InChIKey=NUKQFQCRMMSKDE-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317478   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bombesin (RAT)	BDBM50317478 (5-(azocan-1-yl)-7-benzyl-6,7,8,9-tetrahydro-3H-pyr...) Show SMILES Nc1n[nH]c2nc(N3CCCCCCC3)c3CN(Cc4ccccc4)CCc3c12 Show InChI InChI=1S/C23H30N6/c24-21-20-18-11-14-28(15-17-9-5-4-6-10-17)16-19(18)23(25-22(20)27-26-21)29-12-7-2-1-3-8-13-29/h4-6,9-10H,1-3,7-8,11-16H2,(H3,24,25,26,27)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay				Bioorg Med Chem Lett 20: 2785-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.065 BindingDB Entry DOI: 10.7270/Q2NZ88K4
					More data for this Ligand-Target Pair
BRS3 (Homo sapiens (Human))	BDBM50317478 (5-(azocan-1-yl)-7-benzyl-6,7,8,9-tetrahydro-3H-pyr...) Show SMILES Nc1n[nH]c2nc(N3CCCCCCC3)c3CN(Cc4ccccc4)CCc3c12 Show InChI InChI=1S/C23H30N6/c24-21-20-18-11-14-28(15-17-9-5-4-6-10-17)16-19(18)23(25-22(20)27-26-21)29-12-7-2-1-3-8-13-29/h4-6,9-10H,1-3,7-8,11-16H2,(H3,24,25,26,27)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Agonist activity at human BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay				Bioorg Med Chem Lett 20: 2785-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.065 BindingDB Entry DOI: 10.7270/Q2NZ88K4
					More data for this Ligand-Target Pair