BDBM50323250 1-methyl-6-(4-(2-(piperidin-4-yl)ethoxy)-3-(trifluoromethyl)phenyl)-1H-imidazo[4,5-c]pyridine-4-carbonitrile::CHEMBL1209037::US9115126, WO 2009/010491, Example 14a

SMILES: Cn1cnc2c(nc(cc12)-c1ccc(OCCC2CCNCC2)c(c1)C(F)(F)F)C#N

InChI Key: InChIKey=PBHZOHMBRYRIGB-UHFFFAOYSA-N

Data: 10 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50323250   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin S (Human)	BDBM50323250 (1-methyl-6-(4-(2-(piperidin-4-yl)ethoxy)-3-(triflu...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin S (Human)	BDBM50323250 (1-methyl-6-(4-(2-(piperidin-4-yl)ethoxy)-3-(triflu...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin K (Human)	BDBM50323250 (1-methyl-6-(4-(2-(piperidin-4-yl)ethoxy)-3-(triflu...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	178	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin S (Human)	BDBM50323250 (1-methyl-6-(4-(2-(piperidin-4-yl)ethoxy)-3-(triflu...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin S (Human)	BDBM50323250 (1-methyl-6-(4-(2-(piperidin-4-yl)ethoxy)-3-(triflu...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin S (Human)	BDBM50323250 (1-methyl-6-(4-(2-(piperidin-4-yl)ethoxy)-3-(triflu...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin L2 (Human)	BDBM50323250 (1-methyl-6-(4-(2-(piperidin-4-yl)ethoxy)-3-(triflu...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Procathepsin L (Human)	BDBM50323250 (1-methyl-6-(4-(2-(piperidin-4-yl)ethoxy)-3-(triflu...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin K (Human)	BDBM50323250 (1-methyl-6-(4-(2-(piperidin-4-yl)ethoxy)-3-(triflu...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	178	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin B (Human)	BDBM50323250 (1-methyl-6-(4-(2-(piperidin-4-yl)ethoxy)-3-(triflu...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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