BDBM50328192 CHEMBL1257781::N-(4-(Trifluoromethoxy)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine::US9670214, TABLE 12.2

SMILES: FC(F)(F)Oc1ccc(Nc2ncnc3[nH]ccc23)cc1

InChI Key: InChIKey=JIHDZQXFAZNODD-UHFFFAOYSA-N

Data: 4 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50328192   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Non-specific protein-tyrosine kinase (Human)	BDBM50328192 (N-(4-(Trifluoromethoxy)phenyl)-7H-pyrrolo[2,3-d]py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
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Non-specific protein-tyrosine kinase [T818I] (Human)	BDBM50328192 (N-(4-(Trifluoromethoxy)phenyl)-7H-pyrrolo[2,3-d]py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
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Tau-tubulin kinase 1 (Human)	BDBM50328192 (N-(4-(Trifluoromethoxy)phenyl)-7H-pyrrolo[2,3-d]py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tau-tubulin kinase 2 (Human)	BDBM50328192 (N-(4-(Trifluoromethoxy)phenyl)-7H-pyrrolo[2,3-d]py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Breakpoint cluster region protein/Tyrosine-protein kinase ABL1 (Human)	BDBM50328192 (N-(4-(Trifluoromethoxy)phenyl)-7H-pyrrolo[2,3-d]py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair