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BDBM50334528 1-benzyl-3-(4-fluorophenyl)-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine::CHEMBL1644279

SMILES: Fc1ccc(cc1)-c1cn(Cc2ccccc2)c2CCNCc12

InChI Key: InChIKey=CIWSCWZVBRNILW-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50334528   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50334528
PNG
(1-benzyl-3-(4-fluorophenyl)-4,5,6,7-tetrahydro-1H-...)
Show SMILES Fc1ccc(cc1)-c1cn(Cc2ccccc2)c2CCNCc12
Show InChI InChI=1S/C20H19FN2/c21-17-8-6-16(7-9-17)19-14-23(13-15-4-2-1-3-5-15)20-10-11-22-12-18(19)20/h1-9,14,22H,10-13H2
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Similars

Article
PubMed
45n/an/an/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]5-CT from rat recombinant 5HT7 receptor expressed in HEK293 cells after 60 mins


Bioorg Med Chem Lett 21: 42-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.11.078
BindingDB Entry DOI: 10.7270/Q2M908Z5
More data for this
Ligand-Target Pair