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BDBM50339069 CHEMBL1688373::methyl 2-(4-(2-(benzyloxy)acetyl)piperazin-1-yl)benzoate

SMILES: COC(=O)c1ccccc1N1CCN(CC1)C(=O)COCc1ccccc1

InChI Key: InChIKey=AXXDRLJMHXYFJW-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339069   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor


(Rattus norvegicus (Rat))
BDBM50339069
PNG
(CHEMBL1688373 | methyl 2-(4-(2-(benzyloxy)acetyl)p...)
Show SMILES COC(=O)c1ccccc1N1CCN(CC1)C(=O)COCc1ccccc1
Show InChI InChI=1S/C21H24N2O4/c1-26-21(25)18-9-5-6-10-19(18)22-11-13-23(14-12-22)20(24)16-27-15-17-7-3-2-4-8-17/h2-10H,11-16H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Positive allosteric modulation at rat mGluR5 receptor expressed in HEK293 cells assessed as glutamate-induced calcium fluorescence by Fluo-4/AM dye-b...


ACS Med Chem Lett 1: 433-438 (2010)


Article DOI: 10.1021/ml100181a
BindingDB Entry DOI: 10.7270/Q2DJ5FX7
More data for this
Ligand-Target Pair