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BDBM50375146 CHEMBL271460

SMILES: NC(=O)c1cn(-c2ccc3CCCc3c2)c2nc(Nc3ccccc3)ncc2c1=O

InChI Key: InChIKey=JLTJDHQELMYFGK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50375146   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM50375146
PNG
(CHEMBL271460)
Show SMILES NC(=O)c1cn(-c2ccc3CCCc3c2)c2nc(Nc3ccccc3)ncc2c1=O
Show InChI InChI=1S/C23H19N5O2/c24-21(30)19-13-28(17-10-9-14-5-4-6-15(14)11-17)22-18(20(19)29)12-25-23(27-22)26-16-7-2-1-3-8-16/h1-3,7-13H,4-6H2,(H2,24,30)(H,25,26,27)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 280n/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL


Assay Description
Inhibition of ATP-induced CSF1R autophosphorylation


Bioorg Med Chem Lett 18: 2355-61 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.070
BindingDB Entry DOI: 10.7270/Q26W9BX3
More data for this
Ligand-Target Pair