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BDBM50415767 CHEMBL1077276

SMILES: Nc1nc2C(CCCCc2c(n1)N1CC2CCCNC2C1)c1ccccc1

InChI Key: InChIKey=KMYVBYYBQAUEAL-UHFFFAOYNA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50415767   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 Receptor


(Rattus norvegicus (rat))
BDBM50415767
PNG
(CHEMBL1077276)
Show SMILES Nc1nc2C(CCCCc2c(n1)N1CC2CCCNC2C1)c1ccccc1
Show InChI InChI=1/C22H29N5/c23-22-25-20-17(15-7-2-1-3-8-15)10-4-5-11-18(20)21(26-22)27-13-16-9-6-12-24-19(16)14-27/h1-3,7-8,16-17,19,24H,4-6,9-14H2,(H2,23,25,26)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.69n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-histamine from rat histamine H4 receptor after 1 hr by liquid scintillation counting


Bioorg Med Chem Lett 20: 1900-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.131
BindingDB Entry DOI: 10.7270/Q21V5G6X
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50415767
PNG
(CHEMBL1077276)
Show SMILES Nc1nc2C(CCCCc2c(n1)N1CC2CCCNC2C1)c1ccccc1
Show InChI InChI=1/C22H29N5/c23-22-25-20-17(15-7-2-1-3-8-15)10-4-5-11-18(20)21(26-22)27-13-16-9-6-12-24-19(16)14-27/h1-3,7-8,16-17,19,24H,4-6,9-14H2,(H2,23,25,26)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
7.08n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-histamine from human histamine H4 receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting


Bioorg Med Chem Lett 20: 1900-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.131
BindingDB Entry DOI: 10.7270/Q21V5G6X
More data for this
Ligand-Target Pair