BDBM21015 (2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]-N-methylacetamido}-N-(2-hydroxyethyl)-3-phenylpropanamide::2-Ala-4-MePhe-5-Gly-Enkephalin::CHEMBL38874::D-Ala2-MePhe4-Met(0)5-enkephalin-ol::DAMGO::RX 783006::US11492374, ID 2::US11912716, Compound DAMGO::US20240092802, Compound DAMGO::[3H]DAMGO::[tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephalin

SMILES: C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)NCCO

InChI Key: InChIKey=HPZJMUBDEAMBFI-UHFFFAOYSA-N

Data: 140 KI  32 IC50  9 Kd  99 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 277 hits for monomerid = 21015   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Rat)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.5	37	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.850	37	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.850	37	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.294	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.07	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Mouse)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.98	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	146	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Mouse)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Mouse)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Guinea pig)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Mouse)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.260	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rat)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	49	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	33	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Mouse)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Mouse)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Mouse)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.60	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.794	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Mouse)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	88	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.20	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	75	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Mouse)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	44	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.10	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type/Mu-type opioid receptor (Mouse)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type/Mu-type opioid receptor (Mouse)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	83	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Mouse)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Mouse)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.490	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.490	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21015 ([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	182	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair