BDBM8986 7-chloro-1,2,3,4-tetrahydroacridin-9-amine::Tacrine Analogue 3

SMILES: Nc1c2CCCCc2nc2ccc(Cl)cc12

InChI Key: InChIKey=PUKKYURTEBJMKJ-UHFFFAOYSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 8986   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Human)	BDBM8986 (7-chloro-1,2,3,4-tetrahydroacridin-9-amine | Tacri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	550	n/a	n/a	n/a	n/a	8.0	37
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Acetylcholinesterase (Human)	BDBM8986 (7-chloro-1,2,3,4-tetrahydroacridin-9-amine | Tacri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Human)	BDBM8986 (7-chloro-1,2,3,4-tetrahydroacridin-9-amine | Tacri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glutamate receptor ionotropic, NMDA 1/2A (Human)	BDBM8986 (7-chloro-1,2,3,4-tetrahydroacridin-9-amine | Tacri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.48E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Neuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4 (Rat)	BDBM8986 (7-chloro-1,2,3,4-tetrahydroacridin-9-amine | Tacri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM8986 (7-chloro-1,2,3,4-tetrahydroacridin-9-amine | Tacri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Carboxylic ester hydrolase (Horse)	BDBM8986 (7-chloro-1,2,3,4-tetrahydroacridin-9-amine | Tacri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM8986 (7-chloro-1,2,3,4-tetrahydroacridin-9-amine | Tacri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	743	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Electric eel)	BDBM8986 (7-chloro-1,2,3,4-tetrahydroacridin-9-amine | Tacri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM8986 (7-chloro-1,2,3,4-tetrahydroacridin-9-amine | Tacri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM8986 (7-chloro-1,2,3,4-tetrahydroacridin-9-amine | Tacri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	741	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM8986 (7-chloro-1,2,3,4-tetrahydroacridin-9-amine | Tacri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair