TargetOrotidine 5'-phosphate decarboxylase(Saccharomyces cerevisiae)
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataKi: 0.00880nMAssay Description:Inhibition of Saccharomyces cerevisia uridine 5'-monophosphate synthaseMore data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Saccharomyces cerevisiae)
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataKi: 0.00900nM ΔG°: -63.0kJ/moleT: 2°CAssay Description:Inhibition of Saccharomyces cerevisia uridine 5'-monophosphate synthase after overnight incubation at room temperature by VP-ITC microcalorimetryMore data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Saccharomyces cerevisiae)
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataKi: 5nM ΔG°: -47.4kJ/moleT: 2°CAssay Description:Inhibition of Saccharomyces cerevisia uridine 5'-monophosphate synthase after overnight incubation at room temperature by VP-ITC microcalorimetryMore data for this Ligand-Target Pair
TargetUridine 5'-monophosphate synthase(Homo sapiens (Human))
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataKi: 17nM ΔG°: -44.3kJ/moleT: 2°CAssay Description:Inhibition of human uridine 5'-monophosphate synthase after overnight incubation at room temperature by UV spectroscopyMore data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Saccharomyces cerevisiae)
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataKi: 64nMAssay Description:Inhibition of Saccharomyces cerevisiae ODCase at 25 degreeC by competitive binding assayMore data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute
Toronto General Research Institute
Affinity DataKi: 190nM ΔG°: -42.2kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute
Toronto General Research Institute
Affinity DataKi: 200nM ΔG°: -42.1kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
TargetUridine 5'-monophosphate synthase(Homo sapiens (Human))
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataKi: 350nM ΔG°: -38.3kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute
Toronto General Research Institute
Affinity DataKi: 360nM ΔG°: -40.5kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Saccharomyces cerevisiae)
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Inhibition of yeast ODCaseMore data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute
Toronto General Research Institute
Affinity DataKi: 630nMAssay Description:Irreversible inhibition of Methanobacterium thermoautotrophicum 5'-monophosphate decarboxylaseMore data for this Ligand-Target Pair
Affinity DataKi: 800nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 800nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute
Toronto General Research Institute
Affinity DataKi: 840nM ΔG°: -38.2kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute
Toronto General Research Institute
Affinity DataKi: 840nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCase at 55 degreeC by competitive binding assayMore data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute
Toronto General Research Institute
Affinity DataKi: 840nM ΔG°: -38.2kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition of Plasmodium falciparum ODCase at 25 degreeC by competitive binding assayMore data for this Ligand-Target Pair
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 1.10E+3nM ΔG°: -35.4kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 2.00E+3nM ΔG°: -33.8kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 2.10E+3nM ΔG°: -33.7kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
Affinity DataKi: 2.53E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.20E+3nMAssay Description:Beta-lactam compounds were assessed as competitive inhibitors using nitrocefin as a reporter substrate.More data for this Ligand-Target Pair
Affinity DataKi: 3.29E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.60E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.20E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.00E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.49E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.60E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.06E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute
Toronto General Research Institute
Affinity DataKi: 1.11E+4nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute
Toronto General Research Institute
Affinity DataKi: 1.14E+4nM ΔG°: -31.1kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute
Toronto General Research Institute
Affinity DataKi: 1.24E+4nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCase at 55 degreeC by competitive binding assayMore data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute
Toronto General Research Institute
Affinity DataKi: 1.24E+4nM ΔG°: -30.8kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
Affinity DataKi: 1.36E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
TargetUridine 5'-monophosphate synthase(Homo sapiens (Human))
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataKi: 1.66E+4nM ΔG°: -28.4kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
Affinity DataKi: 1.97E+4nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
Affinity DataKi: 2.13E+4nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 2.21E+4nMAssay Description:Inhibition of Plasmodium falciparum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium vivax (malaria parasite P. vivax))
Toronto General Research Institute
Toronto General Research Institute
Affinity DataKi: 2.24E+4nMpH: 7.5Assay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair