Compile Data Set for Download or QSAR
maximum 50k data
Found 189 with Last Name = 'kotra' and Initial = 'lp'
TargetOrotidine 5'-phosphate decarboxylase(Saccharomyces cerevisiae)
University Health Network

Curated by ChEMBL
LigandPNGBDBM50199178(1-beta-D-ribofuranosyl(3H)pyrimidine-2,4,6-trione ...)
Affinity DataKi:  0.00880nMAssay Description:Inhibition of Saccharomyces cerevisia uridine 5'-monophosphate synthaseMore data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Saccharomyces cerevisiae)
University Health Network

Curated by ChEMBL
LigandPNGBDBM50199178(1-beta-D-ribofuranosyl(3H)pyrimidine-2,4,6-trione ...)
Affinity DataKi:  0.00900nM ΔG°:  -63.0kJ/moleT: 2°CAssay Description:Inhibition of Saccharomyces cerevisia uridine 5'-monophosphate synthase after overnight incubation at room temperature by VP-ITC microcalorimetryMore data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Saccharomyces cerevisiae)
University Health Network

Curated by ChEMBL
LigandPNGBDBM50378784(CHEMBL1164953)
Affinity DataKi:  5nM ΔG°:  -47.4kJ/moleT: 2°CAssay Description:Inhibition of Saccharomyces cerevisia uridine 5'-monophosphate synthase after overnight incubation at room temperature by VP-ITC microcalorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine 5'-monophosphate synthase(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50378784(CHEMBL1164953)
Affinity DataKi:  17nM ΔG°:  -44.3kJ/moleT: 2°CAssay Description:Inhibition of human uridine 5'-monophosphate synthase after overnight incubation at room temperature by UV spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine 5'-phosphate decarboxylase(Saccharomyces cerevisiae)
University Health Network

Curated by ChEMBL
LigandPNGBDBM21340(6-aza-UMP | C6-Uridine Derivative, 18 | {[(2R,3S,4...)
Affinity DataKi:  64nMAssay Description:Inhibition of Saccharomyces cerevisiae ODCase at 25 degreeC by competitive binding assayMore data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21337(6-Azido-uridine 5-O-Monophosphate | C6-Uridine Der...)
Affinity DataKi:  190nM ΔG°:  -42.2kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetFalcipain 2(Plasmodium falciparum)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50074428(CHEMBL3409895)
Affinity DataKi:  200nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21337(6-Azido-uridine 5-O-Monophosphate | C6-Uridine Der...)
Affinity DataKi:  200nM ΔG°:  -42.1kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetFalcipain 2(Plasmodium falciparum)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50074133(CHEMBL3409912)
Affinity DataKi:  300nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50074132(CHEMBL3409913)
Affinity DataKi:  300nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine 5'-monophosphate synthase(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM27946(uridine derivative, 43 | {[(2R,3S,4R,5R)-5-(6-ethy...)
Affinity DataKi:  350nM ΔG°:  -38.3kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM27944(uridine derivative, 41 | {[(2R,3S,4R,5R)-5-(6-azid...)
Affinity DataKi:  360nM ΔG°:  -40.5kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine 5'-phosphate decarboxylase(Saccharomyces cerevisiae)
University Health Network

Curated by ChEMBL
LigandPNGBDBM50231945(CHEMBL253328 | xanthosine-5'-monophosphate disodiu...)
Affinity DataKi:  400nMAssay Description:Inhibition of yeast ODCaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50074144(CHEMBL3409901)
Affinity DataKi:  400nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50074143(CHEMBL3409902)
Affinity DataKi:  400nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50074130(CHEMBL3409915)
Affinity DataKi:  600nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM50341908(((2S,3S,4R,5R)-5-(5-azido-2,4-dioxo-3,4-dihydropyr...)
Affinity DataKi:  630nMAssay Description:Irreversible inhibition of Methanobacterium thermoautotrophicum 5'-monophosphate decarboxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50074131(CHEMBL3409914)
Affinity DataKi:  800nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50074145(CHEMBL3409900)
Affinity DataKi:  800nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21338(6-Amino-uridine 5-O-Monophosphate | C6-Uridine Der...)
Affinity DataKi:  840nM ΔG°:  -38.2kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21338(6-Amino-uridine 5-O-Monophosphate | C6-Uridine Der...)
Affinity DataKi:  840nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCase at 55 degreeC by competitive binding assayMore data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21338(6-Amino-uridine 5-O-Monophosphate | C6-Uridine Der...)
Affinity DataKi:  840nM ΔG°:  -38.2kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM21340(6-aza-UMP | C6-Uridine Derivative, 18 | {[(2R,3S,4...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of Plasmodium falciparum ODCase at 25 degreeC by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM21340(6-aza-UMP | C6-Uridine Derivative, 18 | {[(2R,3S,4...)
Affinity DataKi:  1.10E+3nM ΔG°:  -35.4kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50074138(CHEMBL3409907)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50074137(CHEMBL3409908)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50074434(CHEMBL3409894)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM21337(6-Azido-uridine 5-O-Monophosphate | C6-Uridine Der...)
Affinity DataKi:  2.00E+3nM ΔG°:  -33.8kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM21338(6-Amino-uridine 5-O-Monophosphate | C6-Uridine Der...)
Affinity DataKi:  2.10E+3nM ΔG°:  -33.7kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetFalcipain 2(Plasmodium falciparum)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50074142(CHEMBL3409903)
Affinity DataKi:  2.53E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxa40(Acinetobacter baumannii)
York University

LigandPNGBDBM92463(Imipenem)
Affinity DataKi:  3.20E+3nMAssay Description:Beta-lactam compounds were assessed as competitive inhibitors using nitrocefin as a reporter substrate.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50074141(CHEMBL3409904)
Affinity DataKi:  3.29E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50074139(CHEMBL3409906)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50074326(CHEMBL3409897)
Affinity DataKi:  6.20E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50074146(CHEMBL3409899)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50074140(CHEMBL3409905)
Affinity DataKi:  7.49E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50074129(CHEMBL3410086)
Affinity DataKi:  8.60E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50074135(CHEMBL3409910)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50074136(CHEMBL3409909)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50074212(CHEMBL3409898)
Affinity DataKi:  1.06E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM50398698(CHEMBL2178721)
Affinity DataKi:  1.11E+4nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM27945(uridine derivative, 42 | {[(2R,3S,4R,5R)-5-(6-amin...)
Affinity DataKi:  1.14E+4nM ΔG°:  -31.1kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21340(6-aza-UMP | C6-Uridine Derivative, 18 | {[(2R,3S,4...)
Affinity DataKi:  1.24E+4nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCase at 55 degreeC by competitive binding assayMore data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21340(6-aza-UMP | C6-Uridine Derivative, 18 | {[(2R,3S,4...)
Affinity DataKi:  1.24E+4nM ΔG°:  -30.8kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetFalcipain 2(Plasmodium falciparum)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50074327(CHEMBL3409896)
Affinity DataKi:  1.36E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 using ZFR-AMC as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine 5'-monophosphate synthase(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM27945(uridine derivative, 42 | {[(2R,3S,4R,5R)-5-(6-amin...)
Affinity DataKi:  1.66E+4nM ΔG°:  -28.4kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-arginine deiminase type-2(Mus musculus)
University Health Network

US Patent
LigandPNGBDBM454161(US10716791, Code KP-226)
Affinity DataKi:  1.97E+4nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-2(Mus musculus)
University Health Network

US Patent
LigandPNGBDBM454160(US10716791, Code KP-224)
Affinity DataKi:  2.13E+4nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50398698(CHEMBL2178721)
Affinity DataKi:  2.21E+4nMAssay Description:Inhibition of Plasmodium falciparum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium vivax (malaria parasite P. vivax))
Toronto General Research Institute

LigandPNGBDBM21339(6-Methyl-uridine 5-O-Monophosphate | C6-Uridine De...)
Affinity DataKi:  2.24E+4nMpH: 7.5Assay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 189 total ) | Next | Last >>
Jump to: