Compile Data Set for Download or QSAR
maximum 50k data
Found 186 with Last Name = 'dao' and Initial = 'jh'
TargetEgl nine homolog 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50251959(2-(2-(2-(4-tert-butylbenzylsulfonyl)acetamido)-3-h...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human PHD2 assesssed as hydroxylation of Pro564 in human HIF-1alpha by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50264220(2-(1,6-diphenyl-1H-imidazo[4,5-c]pyridine-4-carbox...)
Affinity DataIC50:  3nMAssay Description:Inhibition of PHD2 (unknown origin) by fluorescence energy transfer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016163(CHEMBL3261514)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016165(CHEMBL3261516)
Affinity DataIC50:  6nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016166(CHEMBL3261517)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016163(CHEMBL3261514)
Affinity DataIC50:  10nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 2 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016163(CHEMBL3261514)
Affinity DataIC50:  10nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 1 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50251958(2-(2-(2-(benzylsulfonyl)acetamido)-3-hydroxy-2,3-d...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human PHD2 assesssed as hydroxylation of Pro564 in human HIF-1alpha by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016163(CHEMBL3261514)
Affinity DataIC50:  13nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 6 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016163(CHEMBL3261514)
Affinity DataIC50:  14nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 0.667 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016148(CHEMBL3261500)
Affinity DataIC50:  14nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016163(CHEMBL3261514)
Affinity DataIC50:  17nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 0.012 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016161(CHEMBL3261512)
Affinity DataIC50:  18nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016163(CHEMBL3261514)
Affinity DataIC50:  18nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 9 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016160(CHEMBL3261511)
Affinity DataIC50:  18nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016163(CHEMBL3261514)
Affinity DataIC50:  20nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 0.333 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016167(CHEMBL3261518)
Affinity DataIC50:  21nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252002(2-(2-(2-(4-tert-butylphenylsulfonyl)acetamido)-3-h...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human PHD2 assesssed as hydroxylation of Pro564 in human HIF-1alpha by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50251957(CHEMBL519615 | {2-[2-(Biphenyl-4-sulfonyl)-acetyli...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human PHD2 assesssed as hydroxylation of Pro564 in human HIF-1alpha by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016163(CHEMBL3261514)
Affinity DataIC50:  23nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 18 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50251908(2-(3-hydroxy-2-(2-(naphthalen-2-ylsulfonyl)acetami...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human PHD2 assesssed as hydroxylation of Pro564 in human HIF-1alpha by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016163(CHEMBL3261514)
Affinity DataIC50:  29nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 0.111 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50251907(2-(2-(2-(4-chlorophenylsulfonyl)acetamido)-3-hydro...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human PHD2 assesssed as hydroxylation of Pro564 in human HIF-1alpha by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016162(CHEMBL3261513)
Affinity DataIC50:  33nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016163(CHEMBL3261514)
Affinity DataIC50:  35nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 0.222 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016163(CHEMBL3261514)
Affinity DataIC50:  40nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 0.025 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016153(CHEMBL3261505)
Affinity DataIC50:  42nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016163(CHEMBL3261514)
Affinity DataIC50:  44nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 27 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252001(2-(3-hydroxy-2-(2-tosylacetamido)-2,3-dihydrothiaz...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human PHD2 assesssed as hydroxylation of Pro564 in human HIF-1alpha by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016164(CHEMBL3261515)
Affinity DataIC50:  62nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016163(CHEMBL3261514)
Affinity DataIC50:  63nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 0.037 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016163(CHEMBL3261514)
Affinity DataIC50:  64nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 0.074 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50264219(2-(6-chloro-1-phenyl-1H-imidazo[4,5-c]pyridine-4-c...)
Affinity DataIC50:  66nMAssay Description:Inhibition of PHD2 (unknown origin) by fluorescence energy transfer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50251900(2-(3-hydroxy-2-(2-(phenylsulfonyl)acetamido)-2,3-d...)
Affinity DataIC50:  72nMAssay Description:Inhibition of human PHD2 assesssed as hydroxylation of Pro564 in human HIF-1alpha by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50251905(2-(2-(2-(2-chlorophenylsulfonyl)acetamido)-3-hydro...)
Affinity DataIC50:  72nMAssay Description:Inhibition of human PHD2 assesssed as hydroxylation of Pro564 in human HIF-1alpha by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50016163(CHEMBL3261514)
Affinity DataIC50:  84nMAssay Description:Inhibition of CK1delta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016163(CHEMBL3261514)
Affinity DataIC50:  86nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 54 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016147(CHEMBL3261499)
Affinity DataIC50:  96nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50251906(2-(2-(2-(3-chlorophenylsulfonyl)acetamido)-3-hydro...)
Affinity DataIC50:  98nMAssay Description:Inhibition of human PHD2 assesssed as hydroxylation of Pro564 in human HIF-1alpha by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016137(CHEMBL3261489)
Affinity DataIC50:  101nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50016166(CHEMBL3261517)
Affinity DataIC50:  104nMAssay Description:Inhibition of CK1delta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016146(CHEMBL3261498)
Affinity DataIC50:  104nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016136(CHEMBL3261488)
Affinity DataIC50:  115nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016135(CHEMBL3261245)
Affinity DataIC50:  172nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50264174(2-(1-phenyl-1H-imidazo[4,5-c]pyridine-4-carboxamid...)
Affinity DataIC50:  290nMAssay Description:Inhibition of PHD2 (unknown origin) by fluorescence energy transfer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016116(CHEMBL3261228)
Affinity DataIC50:  300nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 0.023 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016116(CHEMBL3261228)
Affinity DataIC50:  316nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 0.75 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016116(CHEMBL3261228)
Affinity DataIC50:  318nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 1.5 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50264175(2-(1-benzyl-1H-imidazo[4,5-c]pyridine-4-carboxamid...)
Affinity DataIC50:  320nMAssay Description:Inhibition of PHD2 (unknown origin) by fluorescence energy transfer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016116(CHEMBL3261228)
Affinity DataIC50:  323nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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