Affinity DataKi: 0.240nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Antagonist activity at rat CB1 receptor in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:Antagonist activity at rat CB1 receptor in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 0.670nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 0.830nMAssay Description:Antagonist activity at rat CB1 receptor in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 0.830nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 0.870nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 0.910nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]-YM 09151 from D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.66nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 1.75nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 1.97nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 2.06nMAssay Description:Antagonist activity at rat CB1 receptor in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 2.84nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:D4 receptor functional activity was measured inhibition of quinpirole stimulated [35S]GTP-gamma-S binding from cell membranes.More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]-YM 09151 from D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]-YM 09151 from D4 receptorMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [3H]prazosin from alpha-1 adrenergic receptor of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]-YM 09151 from D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Displacement of [3H]-YM 09151 from D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 9.81nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]-YM 09151 from D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]-YM 09151 from D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 15.0nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [3H]-YM 09151 from D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]-YM 09151 from D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]-YM 09151 from D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Displacement of [3H]-YM 09151 from D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Displacement of [3H]-YM 09151 from D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 32.3nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Displacement of [3H]-YM 09151 from D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:D2 receptor functional activity was measured through reversal of quinpirole inhibited, forskolin stimulated cAMP production from whole cellsMore data for this Ligand-Target Pair
Affinity DataKi: 65nMAssay Description:Displacement of [3H]-YM 09151 from D4 receptorMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataKi: 88nMAssay Description:Displacement of [3H]prazosin from alpha-1 adrenergic receptor of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 113nMAssay Description:Displacement of [3H]-YM 09151 from D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 116nMAssay Description:Displacement of [3H]-YM 09151 from D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 139nMAssay Description:Displacement of [3H]-YM 09151 from D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 165nMAssay Description:Displacement of [3H]-YM 09151 from D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 201nMAssay Description:Displacement of [3H]-YM 09151 from D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 209nMAssay Description:Displacement of [3H]-YM 09151 from D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Displacement of [3H]-YM 09151 from D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 313nMAssay Description:Displacement of [3H]-YM 09151 from D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 393nMAssay Description:Inhibition of human matriptase using Mes-D-Pro-Arg-AMC.2TFA as substrate incubated for 10 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 398nMAssay Description:Inhibition of recombinant hexahistidine tagged human MT-SP1 (596 to 855 residues) expressed in Escherichia coli BL21 gold (DE3) cells using Boc-Leu-A...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 459nMAssay Description:Inhibition of recombinant hexahistidine tagged human MT-SP1 (596 to 855 residues) expressed in Escherichia coli BL21 gold (DE3) cells using Boc-Leu-A...More data for this Ligand-Target Pair
Ligand Info
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataKi: 490nMAssay Description:Displacement of [3H]prazosin from alpha-1 adrenergic receptor of rat brain homogenateMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataKi: 653nMAssay Description:Displacement of [3H]prazosin from alpha-1 adrenergic receptor of rat brain homogenateMore data for this Ligand-Target Pair