TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity to KDM5B (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity to KDM5B (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity to KDM5B (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity to KDM4A (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity to KDM5B (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Competitive inhibition of N-terminal His6-tagged KDM4C (1 to 352 residues) (unknown origin) expressed in Escherichia coli Rosetta 2(DE3)pLysS using A...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Binding affinity to KDM4A (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Binding affinity to KDM4A (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Binding affinity to KDM5B (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Binding affinity to KDM4A (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Binding affinity to KDM4A (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Binding affinity to KDM4A (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Binding affinity to KDM5B (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Binding affinity to KDM4A (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Binding affinity to KDM5B (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Competitive binding affinity to recombinant 6xHis-tagged JHDM1A (unknown origin) expressed in Escherichia coli BL21 incubated for 30 mins prior to co...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Binding affinity to KDM5B (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Binding affinity to KDM4A (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Competitive inhibition of N-terminal His6-tagged KDM4C (1 to 352 residues) (unknown origin) expressed in Escherichia coli Rosetta 2(DE3)pLysS using A...More data for this Ligand-Target Pair
Affinity DataKi: 185nMAssay Description:Competitive binding affinity to recombinant 6xHis-tagged JHDM1A (unknown origin) expressed in Escherichia coli BL21 incubated for 30 mins prior to co...More data for this Ligand-Target Pair
Affinity DataKi: 683nMAssay Description:Competitive inhibition of N-terminal His6-tagged KDM4C (1 to 352 residues) (unknown origin) expressed in Escherichia coli Rosetta 2(DE3)pLysS using A...More data for this Ligand-Target Pair
Affinity DataKi: 1.97E+3nMAssay Description:Competitive inhibition of human KDM2A expressed in Escherichia coli using 2-oxoglutarate by enzyme kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.98E+3nMAssay Description:Competitive binding affinity to recombinant 6xHis-tagged JHDM1A (unknown origin) expressed in Escherichia coli BL21 incubated for 30 mins prior to co...More data for this Ligand-Target Pair
Affinity DataKi: 1.50E+4nMAssay Description:Competitive binding affinity to recombinant 6xHis-tagged JHDM1A (unknown origin) expressed in Escherichia coli BL21 incubated for 30 mins prior to co...More data for this Ligand-Target Pair
Affinity DataKi: 1.54E+4nMAssay Description:Competitive binding affinity to recombinant 6xHis-tagged JHDM1A (unknown origin) expressed in Escherichia coli BL21 incubated for 30 mins prior to co...More data for this Ligand-Target Pair
Affinity DataKi: 8.50E+4nMAssay Description:Mixed type inhibition of human KDM2A expressed in Escherichia coli assessed inhibition constant for compound-enzyme-substrate complex using methyl ly...More data for this Ligand-Target Pair
Affinity DataIC50: 0.650nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat. no. 784900) using an Echo 555 acoustic dispenser, and dimethyl sulfoxide ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant HDAC4More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of LIMK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:IC50 values were determined using 12 point 2-fold dilutions (starting from 10 μM).More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of KDM4C (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human recombinant HDAC9More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human recombinant HDAC9More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant HDAC7More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat. no. 784900) using an Echo 555 acoustic dispenser, and dimethyl sulfoxide ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human recombinant HDAC4More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human recombinant HDAC9More data for this Ligand-Target Pair