BDBM50049181 2-Butyl-3-(2'-(butyloxycarbonylaminosulphonyl)-biphenyl-4-ylmethyl)-6-(N-isopropyl-N-methyl-aminocarbonylamino)-3H-quinazolin-4-one::4'-[2-Butyl-6-(3-isopropyl-3-methyl-ureido)-4-oxo-4H-quinazolin-3-ylmethyl]-biphenyl-2-sulfonic acid butyloxycarbonylamide(LP-162,393)::CHEMBL74476::L-162393::Quinazolinone Analog
SMILES CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCCC)nc3ccc(NC(=O)N(C)C(C)C)cc3c2=O)cc1
InChI Key InChIKey=AEJPLKVXLXBIJD-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50049181
Affinity DataIC50: 0.240nMAssay Description:Tested in vitro for binding affinity against Angiotensin II receptor, type 1 in rabbit aortic membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.240nMAssay Description:Inhibition of Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:In vivo inhibitory concentration of the compound against AT2 receptor of human adrenal membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibitory activity at Angiotensin II type 2 receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:In vivo inhibitory concentration of the compound against Angiotensin II, type 2 of rat midbrain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.240nMAssay Description:In vivo inhibitory concentration of the compound against Angiotensin II receptor, type 1 of rabbit aorta membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:In vitro for binding affinity against angiotensin II receptor type 2 in rat midbrain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:In vivo inhibitory concentration of the compound against Angiotensin II receptor, type 1 of rat adrenal membraneMore data for this Ligand-Target Pair