BDBM50026472 (CH3)2SO::(methanesulfinyl)methanedimethyl sulfoxide::CHEMBL504::DIMETHYL SULFOXIDE::Dimethylsulfoxid::S(O)Me2::US11866416, Compound DMSO::dimethyl sulfur oxide::dimethyl sulphoxide::dmso::methylsulfinylmethane::sulfinylbis(methane)

SMILES CS(C)=O

InChI Key InChIKey=IAZDPXIOMUYVGZ-UHFFFAOYSA-N

Data  6 KI  3 IC50  7 Kd

PDB links: 4384 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50026472   

TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKi:  1.07E+4nMAssay Description:Binding affinity to Magnetospirillum gryphiswaldense cereblon isoform 4 by measuring baseline corrected normalized fluorescence by MST based assayMore data for this Ligand-Target Pair
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKi:  1.37E+5nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKi:  5.70E+6nMAssay Description:Binding affinity to Magnetospirillum gryphiswaldense cereblon isoform by FRET assayMore data for this Ligand-Target Pair
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKi:  1.10E+7nMAssay Description:Competitive binding affinity to Magnetospirillum gryphiswaldense cereblon isoform 4 by measuring baseline corrected normalized fluorescence by MST ba...More data for this Ligand-Target Pair
TargetCholine O-acetyltransferase(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKi:  2.50E+7nMAssay Description:Compound was evaluated for reversible inhibition of hydrolysis acetylcholine by acetylcholinesterase and represented as KI(com)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKi:  1.37E+8nMAssay Description:Competitive binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKd:  6.48E+8nMAssay Description:Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue Y50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataIC50:  2.64E+5nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataIC50:  2.08E+4nMAssay Description:Binding affinity to Magnetospirillum gryphiswaldense cereblon isoform 4 by measuring baseline corrected normalized fluorescence by MST based assayMore data for this Ligand-Target Pair
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKd:  5.41E+8nMAssay Description:Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue L73More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKd:  6.50E+8nMAssay Description:Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue S85More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKd:  7.19E+8nMAssay Description:Dissociation constant of the compound in BS binding to Insulin-like growth factor binding protein 5 at the residue K91More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKd:  6.10E+8nMAssay Description:Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue L81More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKd:  7.83E+8nMAssay Description:Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue Y86More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBiofilm regulatory protein A(Streptococcus mutans serotype c (strain ATCC 70061...)
Uab Research Foundation

US Patent
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataIC50: >5.00E+5nMAssay Description:A previously reported zymographic assay was utilized for the investigation of Gtf enzymatic activity, as described in Example 1. A 1:100 in fresh 5 m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKd:  9.21E+8nMAssay Description:Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue R87More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed