BDBM7457 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4-one::2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-one::2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromone;dihydrate::CHEMBL31574::Fisetin (14)::Fisetin, 15::fisetin

SMILES: c1cc(c(cc1C2=C(C(=O)c3ccc(cc3O2)O)O)O)O

InChI Key: InChIKey=XHEFDIBZLJXQHF-UHFFFAOYSA-N

Data: 4 KI  42 IC50  3 EC50

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 49 hits for monomerid = 7457   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cruzipain (Trypanosoma cruzi)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier organic anion transporter family member 2B1 (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-1 (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-3 (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-2 (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	891	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase pim-1 (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	851	n/a	n/a	n/a	n/a	n/a	n/a
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Polyunsaturated fatty acid lipoxygenase ALOX15B (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Polyunsaturated fatty acid lipoxygenase ALOX15 (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Polyunsaturated fatty acid lipoxygenase ALOX12 (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 5 activator 1 [99-307] (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	570	n/a	n/a	n/a	n/a	7.0	30
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Cruzipain (Trypanosoma cruzi)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Integrase (Human immunodeficiency virus type 1)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Integrase (Human immunodeficiency virus type 1)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
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3-oxoacyl-acyl-carrier protein reductase (malaria parasite P. falciparum)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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3-hydroxyacyl-[acyl-carrier-protein] dehydratase (malaria parasite P. falciparum)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Enoyl-acyl-carrier protein reductase (malaria parasite P. falciparum)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Xanthine dehydrogenase/oxidase (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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DNA gyrase A/A/B/B tetramer (Escherichia coli (strain K12))	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.89E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Pyruvate kinase PKM (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin homolog/dependent kinase 6 (Human-SaHV-2)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	850	n/a	n/a	n/a	n/a	7.0	30
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Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Spiny starfish)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	790	n/a	n/a	n/a	n/a	7.0	30
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Glycogen synthase kinase-3 beta (Rat)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	30
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Alpha-amylase 1A (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.96E+4	n/a	n/a	n/a	n/a	6.0	22
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Serine/threonine-protein kinase pim-1 (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	850	n/a	n/a	n/a	n/a	7.0	30
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Endoribonuclease toxin MazF (Escherichia coli (strain K12))	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>9.90E+4	n/a	n/a	n/a	n/a
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Endoribonuclease toxin MazF (Escherichia coli (strain K12))	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>9.90E+4	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	37
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Mitogen-activated protein kinase 10 (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	37
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17-beta-hydroxysteroid dehydrogenase type 3 (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.24E+4	n/a	n/a	n/a	n/a	7.45	37
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1-deoxy-D-xylulose 5-phosphate reductoisomerase (Escherichia coli (strain K12))	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dipeptidyl peptidase 3 (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.49E+4	n/a	n/a	n/a	n/a	7.4	37
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Pyruvate kinase PKM (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
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DNA topoisomerase 2-alpha (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.86E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Enoyl-acyl-carrier protein reductase (malaria parasite P. falciparum)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-glucosidase MAL62 (Baker's yeast)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 6 (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
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Casein kinase II subunit alpha 3 (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
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Amyloid-beta precursor protein (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Casein kinase II subunit alpha (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Lactoylglutathione lyase (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		1.32E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		9.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM7457 (2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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