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Compounds Sorted by Binding Data per Compound

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29
30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55
56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81
82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105
106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124
125 127 128 129 130 132 133 134 135 136 137 138 139 140 141 143 144 145 146
147 148 149 150 151 153 154 155 156 159 160 161 163 164 165 168 170 171 173
174 176 178 179 183 184 186 188 189 190 191 192 193 196 198 199 200 203 204
205 206 207 208 209 210 216 220 224 226 227 229 232 237 238 241 243 248 252
253 259 261 270 274 276 277 285 291 303 304 313 318 323 325 328 333 335 337
339 341 353 360 361 365 389 393 398 401 413 433 442 444 445 446 447 448 451
453 454 455 457 458 460 463 465 467 473 477 478 482 484 499 504 505 506 517
521 525 543 549 551 554 591 606 663 691 708 796 804 821 825 833 842 847 854
855 861 873 879 883 887 913 914 925 926 938 947 1010 1027 1050 1052 1081 1082
1099 1115 1130 1133 1206 1262 1543 1639 1903 2029
Compounds Sorted Alphabetically
Compound Name (alphabetical)
Enz. Inhib. Data
ITC Data
Binding Targets
Alternate Compound Names
12 Ki 169 IC50 2 EC50
  • 3',5'-cyclic phosphodiesterase
  • Adenosine receptor A2a
  • Bile salt export pump
  • Calcium channel (Type L)
  • Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
  • Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B
  • Heart phosphodiesterase
  • Homo sapiens phosphodiesterase 2A (PDE2A)
  • Indoleamine 2,3-dioxygenase 1
  • Indoleamine 2,3-dioxygenase 2
  • Multidrug resistance-associated protein 4
  • Multidrug resistance-associated protein 5
  • PDE5A/PDE6C
  • Phosphodiesterase (TcrPDEC)
  • Phosphodiesterase 1
  • Phosphodiesterase 11A
  • Phosphodiesterase 11A (PDE11A)
  • Phosphodiesterase 2 and 5 (PDE2 and PDE5)
  • Phosphodiesterase 2A
  • Phosphodiesterase 3
  • Phosphodiesterase 3 (PDE3)
  • Phosphodiesterase 4
  • Phosphodiesterase 5A
  • Phosphodiesterase 6
  • Phosphodiesterase 6C
  • Phosphodiesterase 6C (PDE6C)
  • Phosphodiesterase 7
  • Phosphodiesterase 8
  • Phosphodiesterase 9A
  • Phosphodiesterase Type 10 (PDE10A)
  • Phosphodiesterase Type 11 (PDE11A)
  • Phosphodiesterase Type 2 (PDE2A)
  • Phosphodiesterase Type 3 (PDE3B)
  • Phosphodiesterase Type 4 (PDE4B)
  • Phosphodiesterase Type 4 (PDE4D)
  • Phosphodiesterase Type 5 (PDE5A)
  • Phosphodiesterase Type 5 (PDE5A) Mutant (del 661-681)
  • Phosphodiesterase Type 5 (PDE5A) Mutant (del 663-678)
  • Phosphodiesterase Type 6 (PDE6)
  • Phosphodiesterase Type 7 (PDE7B)
  • Phosphodiesterase Type 9 (PDE9A)
  • Potassium voltage-gated channel subfamily H member 2
  • Sodium channel protein type 5 subunit alpha
  • Voltage-gated potassium channel beta subunit Mink/subunit Kv7.1
  • Voltage-gated potassium channel subunit Kv4.3
  • cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4A
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D
  • cGMP-specific 3',5'-cyclic phosphodiesterase
  • 5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
  • 5-{2-ethoxy-5-[(4-methylpiperazine-1-)sulfonyl]phenyl}-1-methyl-3-propyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one
  • CHEMBL192
  • SILDENAFIL CITRATE
  • Sildenafil
  • Sildenafil#
  • Viagra
122 Ki 59 IC50 1 Kd 1 EC50
  • 5-HT3A Serotonin Receptor
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 2C (5HT2C)
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Adrenaline alpha1
  • Adrenaline alpha2
  • Adrenergic Alpha
  • Adrenergic receptor alpha-2
  • Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • Bile salt export pump
  • Bile salt export pump (BSEP)
  • CHRM5
  • Calcium channel
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cytochrome P450 2J2
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • DRD1
  • Dopamine receptor
  • Dopamine transporter
  • Envelope glycoprotein
  • Gamma-aminobutyric acid receptor subunit alpha-1
  • HTR6
  • Histamine H1 receptor
  • Histamine H2 receptor
  • Multidrug and toxin extrusion protein 1
  • Multidrug and toxin extrusion protein 2
  • Multidrug resistance-associated protein 4
  • Muscarinic acetylcholine receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • Norepinephrine Monoamine transporters
  • Norepinephrine transporter
  • Pleiotropic ABC efflux transporter of multiple drugs
  • Potassium voltage-gated channel subfamily H member 2
  • Prion protein
  • SLC6A3
  • SLC6A4
  • Serotonin (5-HT) receptor
  • Serotonin 2 (5-HT2) receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sigma non-opioid intracellular receptor 1
  • Sodium channel protein type 7 subunit alpha
  • Sodium channel protein type I I alpha subunit
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
  • Solute carrier family 22 member 2
  • Solute carrier family 22 member 3
  • Sphingomyelin phosphodiesterase
  • Voltage-gated L-type calcium channel
  • adrenergic Alpha2
  • CHEMBL11
  • IMIPRAMINE HYDROCHLORIDE
  • IMIPRAMINE PAMOATE
  • Imipramin