The following drop-down menu allows for the browsing of data by specific biological pathway. This pathway heirarchy has been adopted from that used at Reactome. Each sub-pathway contains both BindingDB and Reactome links. BindingDB links go to binding data for proteins involved in a pathway. Note: Reactome "Reactions", as described on this page: https://reactome.org/userguide, are not included here.

  • Autophagy BindingDB Reatome
  • Cell Cycle BindingDB Reatome
    • Cell Cycle Checkpoints BindingDB Reatome
      • G1/S DNA Damage Checkpoints BindingDB Reatome
        • p53-Dependent G1/S DNA damage checkpoint BindingDB Reatome
          • p53-Dependent G1 DNA Damage Response BindingDB Reatome
            • Stabilization of p53 BindingDB Reatome
              • Autodegradation of the E3 ubiquitin ligase COP1 BindingDB Reatome
            • Transcriptional activation of p53 responsive genes BindingDB Reatome
              • Transcriptional activation of cell cycle inhibitor p21 BindingDB Reatome
        • p53-Independent G1/S DNA damage checkpoint BindingDB Reatome
          • p53-Independent DNA Damage Response BindingDB Reatome
            • Ubiquitin Mediated Degradation of Phosphorylated Cdc25A BindingDB Reatome
      • G2/M Checkpoints BindingDB Reatome
        • Activation of ATR in response to replication stress BindingDB Reatome
        • G2/M DNA damage checkpoint BindingDB Reatome
          • Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex BindingDB Reatome
        • G2/M DNA replication checkpoint BindingDB Reatome
      • Mitotic Spindle Checkpoint BindingDB Reatome
        • Amplification of signal from the kinetochores BindingDB Reatome
          • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal BindingDB Reatome
        • Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components BindingDB Reatome
          • Inactivation of APC/C via direct inhibition of the APC/C complex BindingDB Reatome
    • Cell Cycle, Mitotic BindingDB Reatome
      • M Phase BindingDB Reatome
        • Mitotic Metaphase and Anaphase BindingDB Reatome
          • Mitotic Anaphase BindingDB Reatome
            • Nuclear Envelope (NE) Reassembly BindingDB Reatome
              • Initiation of Nuclear Envelope (NE) Reformation BindingDB Reatome
              • Postmitotic nuclear pore complex (NPC) reformation BindingDB Reatome
              • Sealing of the nuclear envelope (NE) by ESCRT-III BindingDB Reatome
            • Separation of Sister Chromatids BindingDB Reatome
          • Mitotic Metaphase/Anaphase Transition BindingDB Reatome
        • Mitotic Prometaphase BindingDB Reatome
          • Condensation of Prometaphase Chromosomes BindingDB Reatome
          • EML4 and NUDC in mitotic spindle formation BindingDB Reatome
          • Recruitment of NuMA to mitotic centrosomes BindingDB Reatome
          • Resolution of Sister Chromatid Cohesion BindingDB Reatome
        • Mitotic Prophase BindingDB Reatome
          • Condensation of Prophase Chromosomes BindingDB Reatome
          • Golgi Cisternae Pericentriolar Stack Reorganization BindingDB Reatome
          • MASTL Facilitates Mitotic Progression BindingDB Reatome
          • Nuclear Envelope Breakdown BindingDB Reatome
            • Activation of NIMA Kinases NEK9, NEK6, NEK7 BindingDB Reatome
            • Depolymerization of the Nuclear Lamina BindingDB Reatome
            • Nuclear Pore Complex (NPC) Disassembly BindingDB Reatome
        • Mitotic Telophase/Cytokinesis BindingDB Reatome
      • Mitotic G1 phase and G1/S transition BindingDB Reatome
        • G0 and Early G1 BindingDB Reatome
          • Transcription of E2F targets under negative control by DREAM complex BindingDB Reatome
          • Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 BindingDB Reatome
        • G1 Phase BindingDB Reatome
          • Cyclin D associated events in G1 BindingDB Reatome
            • Drug-mediated inhibition of CDK4/CDK6 activity BindingDB Reatome
        • G1/S Transition BindingDB Reatome
          • Activation of the pre-replicative complex BindingDB Reatome
          • Cyclin E associated events during G1/S transition BindingDB Reatome
            • Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes BindingDB Reatome
            • SCF(Skp2)-mediated degradation of p27/p21 BindingDB Reatome
          • E2F mediated regulation of DNA replication BindingDB Reatome
            • E2F-enabled inhibition of pre-replication complex formation BindingDB Reatome
            • Inhibition of replication initiation of damaged DNA by RB1/E2F1 BindingDB Reatome
          • G1/S-Specific Transcription BindingDB Reatome
      • Mitotic G2-G2/M phases BindingDB Reatome
        • G2 Phase BindingDB Reatome
        • G2/M Transition BindingDB Reatome
          • AURKA Activation by TPX2 BindingDB Reatome
          • Centrosome maturation BindingDB Reatome
            • Loss of proteins required for interphase microtubule organization from the centrosome BindingDB Reatome
              • Loss of Nlp from mitotic centrosomes BindingDB Reatome
            • Recruitment of mitotic centrosome proteins and complexes BindingDB Reatome
          • Cyclin A/B1/B2 associated events during G2/M transition BindingDB Reatome
            • Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes BindingDB Reatome
          • FBXL7 down-regulates AURKA during mitotic entry and in early mitosis BindingDB Reatome
          • Interaction between PHLDA1 and AURKA BindingDB Reatome
          • Polo-like kinase mediated events BindingDB Reatome
          • Regulation of PLK1 Activity at G2/M Transition BindingDB Reatome
          • The role of GTSE1 in G2/M progression after G2 checkpoint BindingDB Reatome
      • Regulation of mitotic cell cycle BindingDB Reatome
        • APC/C-mediated degradation of cell cycle proteins BindingDB Reatome
          • APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 BindingDB Reatome
          • Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins BindingDB Reatome
            • APC/C:Cdc20 mediated degradation of mitotic proteins BindingDB Reatome
              • APC/C:Cdc20 mediated degradation of Cyclin B BindingDB Reatome
              • APC/C:Cdc20 mediated degradation of Securin BindingDB Reatome
              • APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint BindingDB Reatome
                • APC-Cdc20 mediated degradation of Nek2A BindingDB Reatome
                • Cdc20:Phospho-APC/C mediated degradation of Cyclin A BindingDB Reatome
            • Phosphorylation of the APC/C BindingDB Reatome
          • Autodegradation of Cdh1 by Cdh1:APC/C BindingDB Reatome
          • Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase BindingDB Reatome
          • Regulation of APC/C activators between G1/S and early anaphase BindingDB Reatome
            • Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components BindingDB Reatome
              • Inactivation of APC/C via direct inhibition of the APC/C complex BindingDB Reatome
            • Phosphorylation of Emi1 BindingDB Reatome
            • SCF-beta-TrCP mediated degradation of Emi1 BindingDB Reatome
      • S Phase BindingDB Reatome
    • Chromosome Maintenance BindingDB Reatome
      • Nucleosome assembly BindingDB Reatome
        • Deposition of new CENPA-containing nucleosomes at the centromere BindingDB Reatome
      • Telomere Maintenance BindingDB Reatome
        • Extension of Telomeres BindingDB Reatome
          • Telomere C-strand (Lagging Strand) Synthesis BindingDB Reatome
            • Polymerase switching on the C-strand of the telomere BindingDB Reatome
            • Processive synthesis on the C-strand of the telomere BindingDB Reatome
              • Removal of the Flap Intermediate from the C-strand BindingDB Reatome
            • Telomere C-strand synthesis initiation BindingDB Reatome
          • Telomere Extension By Telomerase BindingDB Reatome
        • Inhibition of DNA recombination at telomere BindingDB Reatome
        • Packaging Of Telomere Ends BindingDB Reatome
    • Meiosis BindingDB Reatome
  • Cell-Cell communication BindingDB Reatome
    • Cell junction organization BindingDB Reatome
      • Cell-cell junction organization BindingDB Reatome
        • Adherens junctions interactions BindingDB Reatome
          • Regulation of Homotypic Cell-Cell Adhesion BindingDB Reatome
            • Regulation of Expression and Function of Type II Classical Cadherins BindingDB Reatome
              • Regulation of CDH11 Expression and Function BindingDB Reatome
    • Nephrin family interactions BindingDB Reatome
    • Signal regulatory protein family interactions BindingDB Reatome
  • Cellular responses to stimuli BindingDB Reatome
    • Cellular responses to stress BindingDB Reatome
      • Cellular response to chemical stress BindingDB Reatome
      • Cellular response to heat stress BindingDB Reatome
      • HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand BindingDB Reatome
  • Chromatin organization BindingDB Reatome
  • Circadian Clock BindingDB Reatome
    • BMAL1:CLOCK,NPAS2 activates circadian gene expression BindingDB Reatome
    • NR1D1 (REV-ERBA) represses gene expression BindingDB Reatome
    • RORA activates gene expression BindingDB Reatome
  • DNA Repair BindingDB Reatome
    • Base Excision Repair BindingDB Reatome
      • Resolution of Abasic Sites (AP sites) BindingDB Reatome
        • APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway BindingDB Reatome
        • Resolution of AP sites via the multiple-nucleotide patch replacement pathway BindingDB Reatome
          • PCNA-Dependent Long Patch Base Excision Repair BindingDB Reatome
          • POLB-Dependent Long Patch Base Excision Repair BindingDB Reatome
        • Resolution of AP sites via the single-nucleotide replacement pathway BindingDB Reatome
          • Abasic sugar-phosphate removal via the single-nucleotide replacement pathway BindingDB Reatome
    • DNA Damage Bypass BindingDB Reatome
      • Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template BindingDB Reatome
    • DNA Double-Strand Break Repair BindingDB Reatome
      • DNA Double Strand Break Response BindingDB Reatome
        • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks BindingDB Reatome
      • Homology Directed Repair BindingDB Reatome
        • HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) BindingDB Reatome
          • HDR through Single Strand Annealing (SSA) BindingDB Reatome
        • HDR through MMEJ (alt-NHEJ) BindingDB Reatome
      • Nonhomologous End-Joining (NHEJ) BindingDB Reatome
    • Nucleotide Excision Repair BindingDB Reatome
      • Global Genome Nucleotide Excision Repair (GG-NER) BindingDB Reatome
  • DNA Replication BindingDB Reatome
  • Developmental Biology BindingDB Reatome
    • Activation of HOX genes during differentiation BindingDB Reatome
      • Activation of anterior HOX genes in hindbrain development during early embryogenesis BindingDB Reatome
    • Cardiogenesis BindingDB Reatome
    • Gastrulation BindingDB Reatome
      • Epithelial-Mesenchymal Transition (EMT) during gastrulation BindingDB Reatome
      • Formation of axial mesoderm BindingDB Reatome
      • Formation of definitive endoderm BindingDB Reatome
      • Formation of intermediate mesoderm BindingDB Reatome
      • Formation of lateral plate mesoderm BindingDB Reatome
      • Formation of paraxial mesoderm BindingDB Reatome
      • Formation of the anterior neural plate BindingDB Reatome
      • Formation of the posterior neural plate BindingDB Reatome
      • Germ layer formation at gastrulation BindingDB Reatome
      • Specification of the neural plate border BindingDB Reatome
    • Keratinization BindingDB Reatome
      • Formation of the cornified envelope BindingDB Reatome
    • Kidney development BindingDB Reatome
    • LGI-ADAM interactions BindingDB Reatome
    • Maternal to zygotic transition (MZT) BindingDB Reatome
      • Chromatin modifications during the maternal to zygotic transition (MZT) BindingDB Reatome
      • M-decay: degradation of maternal mRNAs by maternally stored factors BindingDB Reatome
      • Replacement of protamines by nucleosomes in the male pronucleus BindingDB Reatome
      • Z-decay: degradation of maternal mRNAs by zygotically expressed factors BindingDB Reatome
      • Zygotic genome activation (ZGA) BindingDB Reatome
    • Myogenesis BindingDB Reatome
    • Nervous system development BindingDB Reatome
    • Regulation of beta-cell development BindingDB Reatome
      • Regulation of gene expression in beta cells BindingDB Reatome
        • AKT-mediated inactivation of FOXO1A BindingDB Reatome
      • Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells BindingDB Reatome
    • Signaling by NODAL BindingDB Reatome
    • Transcriptional regulation of granulopoiesis BindingDB Reatome
    • Transcriptional regulation of pluripotent stem cells BindingDB Reatome
      • POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation BindingDB Reatome
      • POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation BindingDB Reatome
    • Transcriptional regulation of testis differentiation BindingDB Reatome
    • Transcriptional regulation of white adipocyte differentiation BindingDB Reatome
  • Digestion and absorption BindingDB Reatome
  • Disease BindingDB Reatome
    • Diseases of DNA repair BindingDB Reatome
      • Diseases of Base Excision Repair BindingDB Reatome
        • Defective Base Excision Repair Associated with OGG1 BindingDB Reatome
          • Defective OGG1 Substrate Binding BindingDB Reatome
          • Defective OGG1 Substrate Processing BindingDB Reatome
      • Diseases of DNA Double-Strand Break Repair BindingDB Reatome
        • Defective DNA double strand break response due to BARD1 loss of function BindingDB Reatome
        • Defective DNA double strand break response due to BRCA1 loss of function BindingDB Reatome
        • Defective homologous recombination repair (HRR) due to BRCA1 loss of function BindingDB Reatome
        • Defective homologous recombination repair (HRR) due to BRCA2 loss of function BindingDB Reatome
          • Impaired BRCA2 binding to PALB2 BindingDB Reatome
          • Impaired BRCA2 binding to RAD51 BindingDB Reatome
          • Impaired BRCA2 binding to SEM1 (DSS1) BindingDB Reatome
          • Impaired BRCA2 translocation to the nucleus BindingDB Reatome
        • Defective homologous recombination repair (HRR) due to PALB2 loss of function BindingDB Reatome
          • Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function BindingDB Reatome
          • Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function BindingDB Reatome
    • Diseases of Immune System BindingDB Reatome
    • Diseases of cellular response to stress BindingDB Reatome
      • Diseases of Cellular Senescence BindingDB Reatome
        • Evasion of Oncogene Induced Senescence Due to p16INK4A Defects BindingDB Reatome
          • Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 BindingDB Reatome
          • Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 BindingDB Reatome
        • Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects BindingDB Reatome
          • Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 BindingDB Reatome
          • Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 BindingDB Reatome
    • Diseases of hemostasis BindingDB Reatome
      • Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) BindingDB Reatome
        • Defective SERPING1 causes hereditary angioedema BindingDB Reatome
        • Defective factor IX causes hemophilia B BindingDB Reatome
        • Defective factor IX causes thrombophilia BindingDB Reatome
        • Defective factor VIII causes hemophilia A BindingDB Reatome
          • Defective F8 accelerates dissociation of the A2 domain BindingDB Reatome
          • Defective F8 binding to the cell membrane BindingDB Reatome
          • Defective F8 binding to von Willebrand factor BindingDB Reatome
          • Defective F8 cleavage by thrombin BindingDB Reatome
          • Defective F8 secretion BindingDB Reatome
          • Defective F8 sulfation at Y1699 BindingDB Reatome
          • Defective cofactor function of FVIIIa variant BindingDB Reatome
        • Defective factor XII causes hereditary angioedema BindingDB Reatome
      • Defects of platelet adhesion to exposed collagen BindingDB Reatome
        • Defective VWF cleavage by ADAMTS13 variant BindingDB Reatome
        • Enhanced cleavage of VWF variant by ADAMTS13 BindingDB Reatome
    • Diseases of metabolism BindingDB Reatome
      • Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate BindingDB Reatome
      • Defective ACTH causes obesity and POMCD BindingDB Reatome
      • Defects in vitamin and cofactor metabolism BindingDB Reatome
        • Defects in biotin (Btn) metabolism BindingDB Reatome
          • Defective BTD causes biotidinase deficiency BindingDB Reatome
          • Defective HLCS causes multiple carboxylase deficiency BindingDB Reatome
        • Defects in cobalamin (B12) metabolism BindingDB Reatome
      • Diseases associated with surfactant metabolism BindingDB Reatome
      • Diseases of carbohydrate metabolism BindingDB Reatome
      • Diseases of glycosylation BindingDB Reatome
        • Diseases associated with N-glycosylation of proteins BindingDB Reatome
        • Diseases associated with O-glycosylation of proteins BindingDB Reatome
        • Diseases associated with glycosaminoglycan metabolism BindingDB Reatome
          • Defective B3GALT6 causes EDSP2 and SEMDJL1 BindingDB Reatome
          • Defective B3GAT3 causes JDSSDHD BindingDB Reatome
          • Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) BindingDB Reatome
          • Defective B4GALT7 causes EDS, progeroid type BindingDB Reatome
          • Defective EXT1 causes exostoses 1, TRPS2 and CHDS BindingDB Reatome
          • Defective EXT2 causes exostoses 2 BindingDB Reatome
          • Defective HEXA causes GM2G1 BindingDB Reatome
          • Defective HEXB causes GM2G2 BindingDB Reatome
          • Defective PAPSS2 causes SEMD-PA BindingDB Reatome
        • Diseases associated with glycosylation precursor biosynthesis BindingDB Reatome
      • Diseases of nucleotide metabolism BindingDB Reatome
        • Nucleotide catabolism defects BindingDB Reatome
          • Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine BindingDB Reatome
        • Nucleotide salvage defects BindingDB Reatome
          • Defective ADA disrupts (deoxy)adenosine deamination BindingDB Reatome
          • Defective HPRT1 disrupts guanine and hypoxanthine salvage BindingDB Reatome
      • Metabolic disorders of biological oxidation enzymes BindingDB Reatome
      • Phenylketonuria BindingDB Reatome
    • Diseases of mitotic cell cycle BindingDB Reatome
      • Aberrant regulation of mitotic cell cycle due to RB1 defects BindingDB Reatome
        • Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects BindingDB Reatome
          • Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) BindingDB Reatome
          • Defective translocation of RB1 mutants to the nucleus BindingDB Reatome
        • Aberrant regulation of mitotic exit in cancer due to RB1 defects BindingDB Reatome
    • Diseases of programmed cell death BindingDB Reatome
      • Defective Intrinsic Pathway for Apoptosis BindingDB Reatome
        • Loss of Function of TP53 in Cancer BindingDB Reatome
          • Loss of function of TP53 in cancer due to loss of tetramerization ability BindingDB Reatome
        • Neurodegenerative Diseases BindingDB Reatome
          • Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models BindingDB Reatome
      • Defective RIPK1-mediated regulated necrosis BindingDB Reatome
        • Microbial modulation of RIPK1-mediated regulated necrosis BindingDB Reatome
      • Defective pyroptosis BindingDB Reatome
    • Diseases of signal transduction by growth factor receptors and second messengers BindingDB Reatome
      • FLT3 signaling in disease BindingDB Reatome
      • Hh mutants abrogate ligand secretion BindingDB Reatome
        • HHAT G278V doesn't palmitoylate Hh-Np BindingDB Reatome
        • Hh mutants are degraded by ERAD BindingDB Reatome
      • Oncogenic MAPK signaling BindingDB Reatome
        • Paradoxical activation of RAF signaling by kinase inactive BRAF BindingDB Reatome
        • RAS signaling downstream of NF1 loss-of-function variants BindingDB Reatome
        • Signaling by BRAF and RAF1 fusions BindingDB Reatome
        • Signaling by MAP2K mutants BindingDB Reatome
        • Signaling by MAPK mutants BindingDB Reatome
        • Signaling by MRAS-complex mutants BindingDB Reatome
          • Gain-of-function MRAS complexes activate RAF signaling BindingDB Reatome
          • SHOC2 M1731 mutant abolishes MRAS complex function BindingDB Reatome
        • Signaling by RAF1 mutants BindingDB Reatome
        • Signaling by RAS mutants BindingDB Reatome
        • Signaling by high-kinase activity BRAF mutants BindingDB Reatome
        • Signaling by moderate kinase activity BRAF mutants BindingDB Reatome
      • PI3K/AKT Signaling in Cancer BindingDB Reatome
        • Constitutive Signaling by AKT1 E17K in Cancer BindingDB Reatome
        • Constitutive Signaling by Aberrant PI3K in Cancer BindingDB Reatome
        • PTEN Loss of Function in Cancer BindingDB Reatome
      • Signaling by ALK in cancer BindingDB Reatome
        • ALK mutants bind TKIs BindingDB Reatome
        • Drug resistance of ALK mutants BindingDB Reatome
        • Signaling by ALK fusions and activated point mutants BindingDB Reatome
          • Nuclear events stimulated by ALK signaling in cancer BindingDB Reatome
      • Signaling by EGFR in Cancer BindingDB Reatome
        • Signaling by EGFRvIII in Cancer BindingDB Reatome
          • Constitutive Signaling by EGFRvIII BindingDB Reatome
        • Signaling by Ligand-Responsive EGFR Variants in Cancer BindingDB Reatome
          • Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants BindingDB Reatome
        • Signaling by Overexpressed Wild-Type EGFR in Cancer BindingDB Reatome
          • Inhibition of Signaling by Overexpressed EGFR BindingDB Reatome
      • Signaling by ERBB2 in Cancer BindingDB Reatome
        • Constitutive Signaling by Overexpressed ERBB2 BindingDB Reatome
        • Drug resistance in ERBB2 KD mutants BindingDB Reatome
          • Resistance of ERBB2 KD mutants to AEE788 BindingDB Reatome
          • Resistance of ERBB2 KD mutants to afatinib BindingDB Reatome
          • Resistance of ERBB2 KD mutants to lapatinib BindingDB Reatome
          • Resistance of ERBB2 KD mutants to neratinib BindingDB Reatome
          • Resistance of ERBB2 KD mutants to osimertinib BindingDB Reatome
          • Resistance of ERBB2 KD mutants to sapitinib BindingDB Reatome
          • Resistance of ERBB2 KD mutants to tesevatinib BindingDB Reatome
          • Resistance of ERBB2 KD mutants to trastuzumab BindingDB Reatome
        • Drug resistance in ERBB2 TMD/JMD mutants BindingDB Reatome
        • Signaling by ERBB2 ECD mutants BindingDB Reatome
        • Signaling by ERBB2 KD Mutants BindingDB Reatome
        • Signaling by ERBB2 TMD/JMD mutants BindingDB Reatome
      • Signaling by FGFR in disease BindingDB Reatome
      • Signaling by KIT in disease BindingDB Reatome
        • Drug resistance of KIT mutants BindingDB Reatome
        • KIT mutants bind TKIs BindingDB Reatome
        • Signaling by extracellular domain mutants of KIT BindingDB Reatome
        • Signaling by juxtamembrane domain KIT mutants BindingDB Reatome
        • Signaling by kinase domain mutants of KIT BindingDB Reatome
        • Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants BindingDB Reatome
      • Signaling by NOTCH1 in Cancer BindingDB Reatome
        • FBXW7 Mutants and NOTCH1 in Cancer BindingDB Reatome
          • Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling BindingDB Reatome
        • Signaling by NOTCH1 HD Domain Mutants in Cancer BindingDB Reatome
          • Constitutive Signaling by NOTCH1 HD Domain Mutants BindingDB Reatome
        • Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer BindingDB Reatome
          • Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants BindingDB Reatome
        • Signaling by NOTCH1 PEST Domain Mutants in Cancer BindingDB Reatome
          • Constitutive Signaling by NOTCH1 PEST Domain Mutants BindingDB Reatome
        • Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant BindingDB Reatome
          • Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant BindingDB Reatome
      • Signaling by PDGFR in disease BindingDB Reatome
        • Drug resistance of PDGFR mutants BindingDB Reatome
        • PDGFR mutants bind TKIs BindingDB Reatome
        • Signaling by PDGFRA extracellular domain mutants BindingDB Reatome
        • Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants BindingDB Reatome
        • Signaling by cytosolic PDGFRA and PDGFRB fusion proteins BindingDB Reatome
        • Signaling by membrane-tethered fusions of PDGFRA or PDGFRB BindingDB Reatome
      • Signaling by TGF-beta Receptor Complex in Cancer BindingDB Reatome
        • Loss of Function of SMAD2/3 in Cancer BindingDB Reatome
          • SMAD2/3 MH2 Domain Mutants in Cancer BindingDB Reatome
          • SMAD2/3 Phosphorylation Motif Mutants in Cancer BindingDB Reatome
        • Loss of Function of SMAD4 in Cancer BindingDB Reatome
          • SMAD4 MH2 Domain Mutants in Cancer BindingDB Reatome
        • Loss of Function of TGFBR1 in Cancer BindingDB Reatome
        • Loss of Function of TGFBR2 in Cancer BindingDB Reatome
          • TGFBR2 Kinase Domain Mutants in Cancer BindingDB Reatome
          • TGFBR2 MSI Frameshift Mutants in Cancer BindingDB Reatome
      • Signaling by WNT in cancer BindingDB Reatome
        • LGK974 inhibits PORCN BindingDB Reatome
        • Signaling by AMER1 mutants BindingDB Reatome
          • Truncations of AMER1 destabilize the destruction complex BindingDB Reatome
        • Signaling by APC mutants BindingDB Reatome
          • APC truncation mutants are not K63 polyubiquitinated BindingDB Reatome
          • APC truncation mutants have impaired AXIN binding BindingDB Reatome
        • Signaling by AXIN mutants BindingDB Reatome
          • AXIN missense mutants destabilize the destruction complex BindingDB Reatome
        • Signaling by CTNNB1 phospho-site mutants BindingDB Reatome
          • CTNNB1 S33 mutants aren't phosphorylated BindingDB Reatome
          • CTNNB1 S37 mutants aren't phosphorylated BindingDB Reatome
          • CTNNB1 S45 mutants aren't phosphorylated BindingDB Reatome
          • CTNNB1 T41 mutants aren't phosphorylated BindingDB Reatome
        • Signaling by GSK3beta mutants BindingDB Reatome
        • Signaling by LRP5 mutants BindingDB Reatome
        • Signaling by RNF43 mutants BindingDB Reatome
        • Signaling by TCF7L2 mutants BindingDB Reatome
        • XAV939 stabilizes AXIN BindingDB Reatome
    • Diseases of the neuronal system BindingDB Reatome
      • Diseases associated with visual transduction BindingDB Reatome
        • Retinoid cycle disease events BindingDB Reatome
          • Biosynthesis of A2E, implicated in retinal degradation BindingDB Reatome
        • Retinoid metabolism disease events BindingDB Reatome
    • Disorders of Developmental Biology BindingDB Reatome
      • Disorders of Nervous System Development BindingDB Reatome
        • Pervasive developmental disorders BindingDB Reatome
          • Loss of function of MECP2 in Rett syndrome BindingDB Reatome
            • Loss of MECP2 binding ability to 5mC-DNA BindingDB Reatome
            • Loss of MECP2 binding ability to the NCoR/SMRT complex BindingDB Reatome
            • Loss of phosphorylation of MECP2 at T308 BindingDB Reatome
    • Disorders of transmembrane transporters BindingDB Reatome
      • ABC transporter disorders BindingDB Reatome
        • Defective ABCB11 causes PFIC2 and BRIC2 BindingDB Reatome
        • Defective ABCB4 causes PFIC3, ICP3 and GBD1 BindingDB Reatome
        • Defective ABCB6 causes MCOPCB7 BindingDB Reatome
        • Defective ABCC2 causes DJS BindingDB Reatome
        • Defective ABCC8 can cause hypo- and hyper-glycemias BindingDB Reatome
        • Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome BindingDB Reatome
        • Defective CFTR causes cystic fibrosis BindingDB Reatome
      • SLC transporter disorders BindingDB Reatome
        • Defective AVP does not bind AVPR1A,B and causes neurohypophyseal diabetes insipidus (NDI) BindingDB Reatome
        • Defective AVP does not bind AVPR2 and causes neurohypophyseal diabetes insipidus (NDI) BindingDB Reatome
        • Defective CP causes aceruloplasminemia (ACERULOP) BindingDB Reatome
        • Defective GCK causes maturity-onset diabetes of the young 2 (MODY2) BindingDB Reatome
        • Defective HK1 causes hexokinase deficiency (HK deficiency) BindingDB Reatome
        • Defective SLC11A2 causes hypochromic microcytic anemia, with iron overload 1 (AHMIO1) BindingDB Reatome
        • Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT) BindingDB Reatome
        • Defective SLC17A5 causes Salla disease (SD) and ISSD BindingDB Reatome
        • Defective SLC1A1 is implicated in schizophrenia 18 (SCZD18) and dicarboxylic aminoaciduria (DCBXA) BindingDB Reatome
        • Defective SLC1A3 causes episodic ataxia 6 (EA6) BindingDB Reatome
        • Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) BindingDB Reatome
        • Defective SLC22A12 causes renal hypouricemia 1 (RHUC1) BindingDB Reatome
        • Defective SLC22A5 causes systemic primary carnitine deficiency (CDSP) BindingDB Reatome
        • Defective SLC26A4 causes Pendred syndrome (PDS) BindingDB Reatome
        • Defective SLC27A4 causes ichthyosis prematurity syndrome (IPS) BindingDB Reatome
        • Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1) BindingDB Reatome
        • Defective SLC2A2 causes Fanconi-Bickel syndrome (FBS) BindingDB Reatome
        • Defective SLC2A9 causes hypouricemia renal 2 (RHUC2) BindingDB Reatome
        • Defective SLC33A1 causes spastic paraplegia 42 (SPG42) BindingDB Reatome
        • Defective SLC34A1 causes hypophosphatemic nephrolithiasis/osteoporosis 1 (NPHLOP1) BindingDB Reatome
        • Defective SLC34A3 causes Hereditary hypophosphatemic rickets with hypercalciuria (HHRH) BindingDB Reatome
        • Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) BindingDB Reatome
        • Defective SLC40A1 causes hemochromatosis 4 (HFE4) (macrophages) BindingDB Reatome
        • Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) BindingDB Reatome
        • Defective SLC5A2 causes renal glucosuria (GLYS1) BindingDB Reatome
        • Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A) BindingDB Reatome
        • Defective SLC6A2 causes orthostatic intolerance (OI) BindingDB Reatome
        • Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) BindingDB Reatome
        • Defective SLC6A5 causes hyperekplexia 3 (HKPX3) BindingDB Reatome
        • Defective SLCO1B1 causes hyperbilirubinemia, Rotor type (HBLRR) BindingDB Reatome
        • Defective SLCO1B3 causes hyperbilirubinemia, Rotor type (HBLRR) BindingDB Reatome
        • Defective SLCO2A1 causes primary, autosomal recessive hypertrophic osteoarthropathy 2 (PHOAR2) BindingDB Reatome
        • Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) BindingDB Reatome
        • Variant SLC6A14 may confer susceptibility towards obesity BindingDB Reatome
    • Infectious disease BindingDB Reatome
      • Bacterial Infection Pathways BindingDB Reatome
        • Infection with Mycobacterium tuberculosis BindingDB Reatome
          • Antimicrobial action and antimicrobial resistance in Mtb BindingDB Reatome
          • Latent infection - Other responses of Mtb to phagocytosis BindingDB Reatome
          • Modulation by Mtb of host immune system BindingDB Reatome
          • Response of Mtb to phagocytosis BindingDB Reatome
        • Listeria monocytogenes entry into host cells BindingDB Reatome
          • InlA-mediated entry of Listeria monocytogenes into host cells BindingDB Reatome
          • InlB-mediated entry of Listeria monocytogenes into host cell BindingDB Reatome
        • Uptake and actions of bacterial toxins BindingDB Reatome
          • Neurotoxicity of clostridium toxins BindingDB Reatome
            • Toxicity of botulinum toxin type A (botA) BindingDB Reatome
            • Toxicity of botulinum toxin type B (botB) BindingDB Reatome
            • Toxicity of botulinum toxin type D (botD) BindingDB Reatome
            • Toxicity of botulinum toxin type E (botE) BindingDB Reatome
            • Toxicity of botulinum toxin type F (botF) BindingDB Reatome
            • Toxicity of tetanus toxin (tetX) BindingDB Reatome
          • Uptake and function of anthrax toxins BindingDB Reatome
          • Uptake and function of diphtheria toxin BindingDB Reatome
      • Parasitic Infection Pathways BindingDB Reatome
        • Leishmania infection BindingDB Reatome
          • Cell recruitment (pro-inflammatory response) BindingDB Reatome
            • Purinergic signaling in leishmaniasis infection BindingDB Reatome
          • Killing mechanisms BindingDB Reatome
            • WNT5:FZD7-mediated leishmania damping BindingDB Reatome
          • Leishmania parasite growth and survival BindingDB Reatome
            • Anti-inflammatory response favouring Leishmania parasite infection BindingDB Reatome
              • ADORA2B mediated anti-inflammatory cytokines production BindingDB Reatome
              • CD163 mediating an anti-inflammatory response BindingDB Reatome
              • FCGR3A-mediated IL10 synthesis BindingDB Reatome
              • LTC4-CYSLTR mediated IL4 production BindingDB Reatome
          • Parasite infection BindingDB Reatome
      • Viral Infection Pathways BindingDB Reatome
        • HCMV Infection BindingDB Reatome
        • HIV Infection BindingDB Reatome
          • HIV Life Cycle BindingDB Reatome
            • Early Phase of HIV Life Cycle BindingDB Reatome
            • Late Phase of HIV Life Cycle BindingDB Reatome
              • Assembly Of The HIV Virion BindingDB Reatome
                • Synthesis And Processing Of GAG, GAGPOL Polyproteins BindingDB Reatome
                  • Membrane binding and targetting of GAG proteins BindingDB Reatome
                • Synthesis and processing of ENV and VPU BindingDB Reatome
              • Budding and maturation of HIV virion BindingDB Reatome
              • Rev-mediated nuclear export of HIV RNA BindingDB Reatome
              • Transcription of the HIV genome BindingDB Reatome
                • Formation of HIV elongation complex in the absence of HIV Tat BindingDB Reatome
                • HIV Transcription Elongation BindingDB Reatome
                  • Abortive elongation of HIV-1 transcript in the absence of Tat BindingDB Reatome
                  • Formation of the HIV-1 Early Elongation Complex BindingDB Reatome
                  • Tat-mediated elongation of the HIV-1 transcript BindingDB Reatome
                    • Formation of HIV-1 elongation complex containing HIV-1 Tat BindingDB Reatome
                • HIV Transcription Initiation BindingDB Reatome
                • HIV elongation arrest and recovery BindingDB Reatome
                • Pausing and recovery of HIV elongation BindingDB Reatome
                • Pausing and recovery of Tat-mediated HIV elongation BindingDB Reatome
                • RNA Pol II CTD phosphorylation and interaction with CE during HIV infection BindingDB Reatome
                • RNA Polymerase II HIV Promoter Escape BindingDB Reatome
                • Tat-mediated HIV elongation arrest and recovery BindingDB Reatome
          • Host Interactions of HIV factors BindingDB Reatome
            • APOBEC3G mediated resistance to HIV-1 infection BindingDB Reatome
            • Interactions of Rev with host cellular proteins BindingDB Reatome
              • Nuclear import of Rev protein BindingDB Reatome
              • Rev-mediated nuclear export of HIV RNA BindingDB Reatome
            • Interactions of Tat with host cellular proteins BindingDB Reatome
            • Interactions of Vpr with host cellular proteins BindingDB Reatome
              • Vpr-mediated nuclear import of PICs BindingDB Reatome
            • The role of Nef in HIV-1 replication and disease pathogenesis BindingDB Reatome
              • Nef and signal transduction BindingDB Reatome
              • Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters BindingDB Reatome
                • Nef Mediated CD4 Down-regulation BindingDB Reatome
                • Nef mediated downregulation of MHC class I complex cell surface expression BindingDB Reatome
            • Vif-mediated degradation of APOBEC3G BindingDB Reatome
            • Vpu mediated degradation of CD4 BindingDB Reatome
        • Influenza Infection BindingDB Reatome
          • Entry of Influenza Virion into Host Cell via Endocytosis BindingDB Reatome
          • Export of Viral Ribonucleoproteins from Nucleus BindingDB Reatome
            • NEP/NS2 Interacts with the Cellular Export Machinery BindingDB Reatome
            • Viral RNP Complexes in the Host Cell Nucleus BindingDB Reatome
          • Fusion and Uncoating of the Influenza Virion BindingDB Reatome
            • Fusion of the Influenza Virion to the Host Cell Endosome BindingDB Reatome
            • Uncoating of the Influenza Virion BindingDB Reatome
          • Influenza Viral RNA Transcription and Replication BindingDB Reatome
          • Influenza Virus Induced Apoptosis BindingDB Reatome
          • NS1 Mediated Effects on Host Pathways BindingDB Reatome
          • Transport of Ribonucleoproteins into the Host Nucleus BindingDB Reatome
          • Virus Assembly and Release BindingDB Reatome
            • Assembly of Viral Components at the Budding Site BindingDB Reatome
              • Transport of HA trimer, NA tetramer and M2 tetramer from the endoplasmic reticulum to the Golgi Apparatus BindingDB Reatome
            • Budding BindingDB Reatome
            • Packaging of Eight RNA Segments BindingDB Reatome
            • Release BindingDB Reatome
        • Respiratory Syncytial Virus Infection Pathway BindingDB Reatome
          • Assembly and release of respiratory syncytial virus (RSV) virions BindingDB Reatome
          • RSV-host interactions BindingDB Reatome
            • Evasion by RSV of host interferon responses BindingDB Reatome
          • Respiratory syncytial virus (RSV) attachment and entry BindingDB Reatome
          • Respiratory syncytial virus (RSV) genome replication, transcription and translation BindingDB Reatome
            • Maturation of hRSV A proteins BindingDB Reatome
            • Respiratory syncytial virus genome replication BindingDB Reatome
            • Respiratory syncytial virus genome transcription BindingDB Reatome
            • Translation of respiratory syncytial virus mRNAs BindingDB Reatome
        • SARS-CoV Infections BindingDB Reatome
          • Potential therapeutics for SARS BindingDB Reatome
          • SARS-CoV-1 Infection BindingDB Reatome
            • Attachment and Entry BindingDB Reatome
            • SARS-CoV-1 Genome Replication and Transcription BindingDB Reatome
              • Replication of the SARS-CoV-1 genome BindingDB Reatome
              • Transcription of SARS-CoV-1 sgRNAs BindingDB Reatome
            • SARS-CoV-1-host interactions BindingDB Reatome
              • SARS-CoV-1 activates/modulates innate immune responses BindingDB Reatome
              • SARS-CoV-1 modulates host translation machinery BindingDB Reatome
              • SARS-CoV-1 targets host intracellular signalling and regulatory pathways BindingDB Reatome
              • SARS-CoV-1-mediated effects on programmed cell death BindingDB Reatome
            • Translation of Replicase and Assembly of the Replication Transcription Complex BindingDB Reatome
              • Assembly of the SARS-CoV-1 Replication-Transcription Complex (RTC) BindingDB Reatome
              • Maturation of replicase proteins BindingDB Reatome
            • Translation of Structural Proteins BindingDB Reatome
            • Virion Assembly and Release BindingDB Reatome
          • SARS-CoV-2 Infection BindingDB Reatome
            • Early SARS-CoV-2 Infection Events BindingDB Reatome
              • Attachment and Entry BindingDB Reatome
              • SARS-CoV-2 Genome Replication and Transcription BindingDB Reatome
                • Replication of the SARS-CoV-2 genome BindingDB Reatome
                • Transcription of SARS-CoV-2 sgRNAs BindingDB Reatome
              • Translation of Replicase and Assembly of the Replication Transcription Complex BindingDB Reatome
                • Assembly of the SARS-CoV-2 Replication-Transcription Complex (RTC) BindingDB Reatome
                • Maturation of replicase proteins BindingDB Reatome
            • Late SARS-CoV-2 Infection Events BindingDB Reatome
            • SARS-CoV-2-host interactions BindingDB Reatome
              • SARS-CoV-2 activates/modulates innate and adaptive immune responses BindingDB Reatome
              • SARS-CoV-2 modulates autophagy BindingDB Reatome
              • SARS-CoV-2 modulates host translation machinery BindingDB Reatome
              • SARS-CoV-2 targets PDZ proteins in cell-cell junction BindingDB Reatome
              • SARS-CoV-2 targets host intracellular signalling and regulatory pathways BindingDB Reatome
  • Drosophila signaling pathways BindingDB Reatome
  • Drug ADME BindingDB Reatome
  • Extracellular matrix organization BindingDB Reatome
  • Gene expression (Transcription) BindingDB Reatome
    • Epigenetic regulation of gene expression BindingDB Reatome
      • Negative epigenetic regulation of rRNA expression BindingDB Reatome
        • SIRT1 negatively regulates rRNA expression BindingDB Reatome
      • PRC2 methylates histones and DNA BindingDB Reatome
    • RNA Polymerase II Transcription BindingDB Reatome
      • Generic Transcription Pathway BindingDB Reatome
        • Nuclear Receptor transcription pathway BindingDB Reatome
        • Transcriptional Regulation by E2F6 BindingDB Reatome
        • Transcriptional Regulation by TP53 BindingDB Reatome
          • Regulation of TP53 Activity BindingDB Reatome
            • Regulation of TP53 Activity through Methylation BindingDB Reatome
  • Hemostasis BindingDB Reatome
    • Cell surface interactions at the vascular wall BindingDB Reatome
    • Dissolution of Fibrin Clot BindingDB Reatome
    • Factors involved in megakaryocyte development and platelet production BindingDB Reatome
    • Formation of Fibrin Clot (Clotting Cascade) BindingDB Reatome
      • Common Pathway of Fibrin Clot Formation BindingDB Reatome
      • Extrinsic Pathway of Fibrin Clot Formation BindingDB Reatome
      • Intrinsic Pathway of Fibrin Clot Formation BindingDB Reatome
    • Platelet Adhesion to exposed collagen BindingDB Reatome
    • Platelet activation, signaling and aggregation BindingDB Reatome
      • Effects of PIP2 hydrolysis BindingDB Reatome
      • GP1b-IX-V activation signalling BindingDB Reatome
      • GPVI-mediated activation cascade BindingDB Reatome
      • Platelet Aggregation (Plug Formation) BindingDB Reatome
        • Adrenaline signalling through Alpha-2 adrenergic receptor BindingDB Reatome
        • Integrin signaling BindingDB Reatome
          • GRB2:SOS provides linkage to MAPK signaling for Integrins BindingDB Reatome
          • p130Cas linkage to MAPK signaling for integrins BindingDB Reatome
      • Response to elevated platelet cytosolic Ca2+ BindingDB Reatome
      • Signal amplification BindingDB Reatome
        • ADP signalling through P2Y purinoceptor 1 BindingDB Reatome
        • ADP signalling through P2Y purinoceptor 12 BindingDB Reatome
        • Thromboxane signalling through TP receptor BindingDB Reatome
      • Thrombin signalling through proteinase activated receptors (PARs) BindingDB Reatome
    • Platelet homeostasis BindingDB Reatome
  • Immune System BindingDB Reatome
  • Metabolism BindingDB Reatome
  • Metabolism of RNA BindingDB Reatome
    • Regulation of mRNA stability by proteins that bind AU-rich elements BindingDB Reatome
      • AUF1 (hnRNP D0) binds and destabilizes mRNA BindingDB Reatome
      • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA BindingDB Reatome
      • HuR (ELAVL1) binds and stabilizes mRNA BindingDB Reatome
      • KSRP (KHSRP) binds and destabilizes mRNA BindingDB Reatome
    • rRNA processing BindingDB Reatome
      • rRNA processing in the nucleus and cytosol BindingDB Reatome
        • Major pathway of rRNA processing in the nucleolus and cytosol BindingDB Reatome
  • Metabolism of proteins BindingDB Reatome
  • Muscle contraction BindingDB Reatome
  • Mycobacterium tuberculosis biological processes BindingDB Reatome
  • Neuronal System BindingDB Reatome
    • Transmission across Chemical Synapses BindingDB Reatome
      • Neurotransmitter receptors and postsynaptic signal transmission BindingDB Reatome
        • Acetylcholine binding and downstream events BindingDB Reatome
          • Postsynaptic nicotinic acetylcholine receptors BindingDB Reatome
            • Highly calcium permeable postsynaptic nicotinic acetylcholine receptors BindingDB Reatome
            • Highly sodium permeable postsynaptic acetylcholine nicotinic receptors BindingDB Reatome
          • Presynaptic nicotinic acetylcholine receptors BindingDB Reatome
            • Highly calcium permeable nicotinic acetylcholine receptors BindingDB Reatome
            • Highly sodium permeable postsynaptic acetylcholine nicotinic receptors BindingDB Reatome
  • Organelle biogenesis and maintenance BindingDB Reatome
  • Programmed Cell Death BindingDB Reatome
  • Protein localization BindingDB Reatome
  • Reproduction BindingDB Reatome
  • Sensory Perception BindingDB Reatome
    • Visual phototransduction BindingDB Reatome
      • The phototransduction cascade BindingDB Reatome
        • Activation of the phototransduction cascade BindingDB Reatome
        • Inactivation, recovery and regulation of the phototransduction cascade BindingDB Reatome
  • Signal Transduction BindingDB Reatome
  • Transport of small molecules BindingDB Reatome
    • O2/CO2 exchange in erythrocytes BindingDB Reatome
      • Erythrocytes take up carbon dioxide and release oxygen BindingDB Reatome
      • Erythrocytes take up oxygen and release carbon dioxide BindingDB Reatome
    • Plasma lipoprotein assembly, remodeling, and clearance BindingDB Reatome
  • Vesicle-mediated transport BindingDB Reatome