Recently Added Targets

1. Mitofusin-2, Human, O95140 (Curated 03/05/23), MFN2: 2 subμM ligands
2. Flavin reductase (NADPH), Human, P30043 (Curated 03/05/23), BLVRB: 4 subμM ligands
3. Biotinidase, Human, P43251 (Curated 03/07/23), BTD: 1 subμM ligands
4. Prolactin-releasing peptide, Human, P81277 (Curated 03/06/23), PRLH: 1 subμM ligands
5. Beclin-1, Human, Q14457 (Curated 03/07/23), BECN1: 5 subμM ligands
6. Bifunctional dihydrofolate reductase-thymidylate synthase, Trypanosoma brucei brucei, Q27783 (Curated 02/16/23), : 11 subμM ligands
7. Vanin 1, Rat, Q4KLZ0 (Curated 03/07/23), Vnn1: 1 subμM ligands
8. Leucine-rich repeat serine/threonine-protein kinase 2, Mouse, Q5S006 (Curated 03/06/23), Lrrk2: 2 subμM ligands
9. Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2, Mouse, Q6P549 (Curated 03/07/23), Inppl1: 1 subμM ligands
10. Cyclic GMP-AMP synthase, Mouse, Q8C6L5 (Curated 03/06/23), Cgas: 2 subμM ligands
11. Presequence protease, mitochondrial, Mouse, Q8K411 (Curated 01/21/23), Pitrm1: 1 subμM ligands
12. Fibroblast activation protein, Rat, Q8R492 (Curated 01/21/23), Fap: 1 subμM ligands
13. Neuropeptide FF receptor 2, Mouse, Q924H0 (Curated 03/06/23), Npffr2: 2 subμM ligands
14. C-type lectin domain family 4 member M, Human, Q9H2X3 (Curated 03/05/23), CLEC4M: 5 subμM ligands
15. Sal-like protein 4, Human, Q9UJQ4 (Curated 02/17/23), SALL4: 11 subμM ligands
16. Nuclear receptor subfamily 2 group E member 1, Human, Q9Y466 (Curated 03/06/23), NR2E1: 3 subμM ligands
17. Sulfide:quinone oxidoreductase, mitochondrial, Human, Q9Y6N5 (Curated 03/04/23), SQOR: 23 subμM ligands
18. Pantetheinase, Mouse, Q9Z0K8 (Curated 03/07/23), Vnn1: 5 subμM ligands

Coronavirus Binding Data

BindingDB has accelerated collection of COVID related data. You can find the result here.

Try the BindingDB Browser Extension

We are excited to share our new browser extension, BDBFind. Once installed in your browser, BDBFind automatically lets you know when BindingDB has the data from an article, PubMed Entry, or US Patent you are looking at online and provides direct links to view or download the data. Get BDBFind by searching for it in the Chrome webstore or in Firefox extensions or by following these links:

• https://chrome.google.com/webstore/search/bdbfind (Once installed, click on the "jigsaw puzzle" icon to keep the BDB icon displayed.)
• https://addons.mozilla.org/addon/bdbfind.

Watch BDBFind in action in this 1.5 minute video: To send feedback about BDBfind, please email us at bindingdb@gmail.com.

BindingDB Data Curation

BindingDB curates US Patents. We have scanned patents back to 2013 for suitable data and are currently up to date as of mid-2020. However, we cannot be sure of capturing all relevant patents, so if you know of a useful one we have missed, please let us know and we will try to curate it. As of March 11, 2023, BindingDB's patent dataset comprises:

1. Patents: 6,303
2. Binding measurements: 972,552
3. Compounds: 469,551
4. Target proteins: 2,453
5. Assays: 9,084
6. Average Number of Targets per Patent: 1.91

BindingDB curates a set of journals not covered by other public databases. As of March 11, 2023, the status of this curation effort is as follows:

• ACS Chemical Biology 2006-2017 (vol 1-12) ^data
• ACS BioChemistry 1965-2017 (vol 4-56) ^data
• Bioorganic Chemistry 1990-2017 (vol 18-73) ^data
• BMC Chemical Biology 2001-2010 (vol 1-10) ^data
• ChemBioChem 2001-2017 (vol 2-18) ^data
• Chemical Biology & Drug Design 2006-2017 (vol 67-89) ^data
• Chemistry & Biology 1995-2015 (vol 2-22) ^data
• Journal of Biological Chemistry 1982-2014 (vol 257-289) ^data
• Journal of Chemical Biology 2010-2010 (vol 3-3) ^data
• Journal of Enzyme Inhibition and Medicinal Chemistry 2002-2014 (vol 17-29) ^data
• Nature Chemical Biology 2005-2017 (vol 1-13) ^data
• Medicinal Chemistry Research 2004-2014 (vol 13-23) ^data