BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.8M data for 1.2M Compounds and 9.2K Targets. Of those, 1,314K data for 602K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

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Recently Added Targets

    1. Prostaglandin reductase 2, Human, Q8N8N7 (Curated 10/17/23), PTGR2: 26 subμM ligands
    2. N6-adenosine-methyltransferase non-catalytic subunit, Human, Q9HCE5 (Curated 09/23/23), METTL14: 144 subμM ligands

BindingDB Archive

BindingDB is archived quarterly at UC San Diego Library Digital Collections.

Coronavirus Binding Data

BindingDB has accelerated collection of COVID related data. You can find the result here.

Try the BindingDB Browser Extension

We are excited to share our new browser extension, BDBFind. Once installed in your browser, BDBFind automatically lets you know when BindingDB has the data from an article, PubMed Entry, or US Patent you are looking at online and provides direct links to view or download the data. Get BDBFind by searching for it in the Chrome webstore or in Firefox extensions or by following these links:

Watch BDBFind in action in this 1.5 minute video: To send feedback about BDBfind, please email us at bindingdb@gmail.com.

BindingDB Data Curation

BindingDB curates US Patents. We have scanned patents back to 2013 for suitable data and are currently up to date as of mid-2020. However, we cannot be sure of capturing all relevant patents, so if you know of a useful one we have missed, please let us know and we will try to curate it. As of November 29, 2023, BindingDB's patent dataset comprises:

  1. Patents: 6,765
  2. Binding measurements: 1,059,214
  3. Compounds: 505,009
  4. Target proteins: 2,578
  5. Assays: 9,728
  6. Average Number of Targets per Patent: 1.92

BindingDB curates a set of journals not covered by other public databases. As of November 29, 2023, the status of this curation effort is as follows:

BindingDB is supported by NIH's National Institute of General Medical Sciences (R24GM144232), and is located at the Skaggs School of Pharmacy and Pharmaceutical Sciences of the University of California San Diego