The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.5M data for 1.1M Compounds and 8.8K Targets. Of those, 1,112K data for 512K Compounds and 4.3K Targets were curated by BindingDB curators.

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Recently Added Targets

    1. glucose-dependent insulinotropic receptor, Golden hamster, A0A1U8CD06 (Curated 03/28/22), Gpr119: 1 subμM ligands
    2. G protein-coupled receptor 34a, Zebrafish, B3DHD6 (Curated 03/28/22), gpr34a: 2 subμM ligands
    3. Histone-lysine N-methyltransferase EZH2, Rat, B5DFE2 (Curated 03/29/22), Ezh2: 1 subμM ligands
    4. Hemagglutinin, Influenza A virus (A/reassortant/NIBRG-121(California/07/2009 x PR8)(H1N1)), C5MVR7 (Curated 03/30/22), HA: 3 subμM ligands
    5. Polyamine deacetylase HDAC10, Zebrafish, F1QCV2 (Curated 03/29/22), hdac10: 1 subμM ligands
    6. Long-chain-fatty-acid--AMP ligase FadD32, Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv), O53580 (Curated 03/29/22), fadD32: 1 subμM ligands
    7. Formyl peptide receptor 2, Mouse, O88536 (Curated 03/28/22), Fpr2: 5 subμM ligands
    8. Carbamate kinase, Giardia intestinalis, O97438 (Curated 03/30/22), CBK: 1 subμM ligands
    9. B-cell lymphoma 6 protein, Human, P41182 (Curated 09/20/19), BCL6: 56 subμM ligands
    10. DNA repair protein RAD52 homolog, Human, P43351 (Curated 03/30/22), RAD52: 1 subμM ligands
    11. Protein farnesyltransferase subunit beta, Human, P49356 (Curated 12/14/14), FNTB: 1373 subμM ligands
    12. Long-chain-fatty-acid--AMP ligase FadD28, Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv), P9WQ59 (Curated 03/29/22), fadD28: 5 subμM ligands
    13. Forkhead box protein M1, Human, Q08050 (Curated 03/28/22), FOXM1: 2 subμM ligands
    14. DNA-binding protein Ikaros, Human, Q13422 (Curated 04/09/22), IKZF1: 4 subμM ligands
    15. 2-hydroxyacylsphingosine 1-beta-galactosyltransferase, Human, Q16880 (Curated 03/28/22), UGT8: 21 subμM ligands
    16. G protein-coupled receptor 34b, Zebrafish, Q568G5 (Curated 03/28/22), gpr34b: 2 subμM ligands
    17. N-terminal Xaa-Pro-Lys N-methyltransferase 2, Human, Q5VVY1 (Curated 03/28/22), NTMT2: 1 subμM ligands
    18. 2-hydroxyacylsphingosine 1-beta-galactosyltransferase, Mouse, Q64676 (Curated 03/28/22), Ugt8: 1 subμM ligands
    19. Relaxin receptor 1, Rat, Q6R6I6 (Curated 03/29/22), Rxfp1: 3 subμM ligands
    20. Neuropeptide FF receptor 1, Rat, Q9EP86 (Curated 03/29/22), Npffr1: 5 subμM ligands

Coronavirus Binding Data

BindingDB has accelerated collection of COVID related data. You can find the result here.

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We are excited to share our new browser extension, BDBFind. Once installed in your browser, BDBFind automatically lets you know when BindingDB has the data from an article, PubMed Entry, or US Patent you are looking at online and provides direct links to view or download the data. Get BDBFind by searching for it in the Chrome webstore or in Firefox extensions or by following these links:

Watch BDBFind in action in this 1.5 minute video: To send feedback about BDBfind, please email us at bindingdb@gmail.com.

BindingDB Data Curation

BindingDB curates US Patents. We have scanned patents back to 2013 for suitable data and are currently up to date as of mid-2020. However, we cannot be sure of capturing all relevant patents, so if you know of a useful one we have missed, please let us know and we will try to curate it. As of May 4, 2022, BindingDB's patent dataset comprises:

  1. Patents: 5,660
  2. Binding measurements: 866,553
  3. Compounds: 418,929
  4. Target proteins: 2,293
  5. Assays: 8,204
  6. Average Number of Targets per Patent: 1.92

BindingDB curates a set of journals not covered by other public databases. As of May 4, 2022, the status of this curation effort is as follows:

BindingDB is supported by NIH's National Institute of General Medical Sciences (GM070064), and is located at the Skaggs School of Pharmacy and Pharmaceutical Sciences of the University of California San Diego