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Compound Name:

Compounds Sorted by Binding Data per Compound

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29
30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55
56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81
82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105
106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124
125 127 128 129 130 132 133 134 135 136 137 138 139 140 141 143 144 145 146
147 148 149 150 151 153 154 155 156 159 160 161 163 164 165 168 170 171 173
174 176 178 179 183 184 186 188 189 190 191 192 193 196 198 199 200 203 204
205 206 207 208 209 210 216 220 224 226 227 229 232 237 238 241 243 248 252
253 259 261 270 274 276 277 285 291 303 304 313 318 323 325 328 333 335 337
339 341 353 360 361 365 389 393 398 401 413 433 442 444 445 446 447 448 451
453 454 455 457 458 460 463 465 467 473 477 478 482 484 499 504 505 506 517
521 525 543 549 551 554 591 606 663 691 708 796 804 821 825 833 842 847 854
855 861 873 879 883 887 913 914 925 926 938 947 1010 1027 1050 1052 1081 1082
1099 1115 1130 1133 1206 1262 1543 1639 1903 2029
Compounds Sorted Alphabetically
Compound Name (alphabetical)
Enz. Inhib. Data
ITC Data
Binding Targets
Alternate Compound Names
18 Ki 46 IC50
  • 72 kDa type IV collagenase
  • Bile salt export pump
  • Collagenase 3
  • Disintegrin and metalloproteinase domain-containing protein 17
  • Interstitial collagenase
  • Matrix metalloproteinase 10
  • Matrix metalloproteinase 14
  • Matrix metalloproteinase 7
  • Matrix metalloproteinase-14 (MMP14)
  • Matrix metalloproteinase-7 (MMP7)
  • Matrix metalloproteinase-9
  • Neutrophil collagenase
  • Stromelysin-1
  • 4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N-hydroxyoxane-4-carboxamide
  • CHEMBL440498
  • RS 130830
  • RS-130,830
  • alpha-tetrahydropyran beta-sulfone 1B
5 Ki 57 IC50 2 EC50
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cannabinoid receptor 1
  • Cannabinoid receptor 2
  • Cholesterol esterase
  • Endothelial lipase
  • Fatty Acid Synthase
  • Fatty acid synthase
  • Fatty-acid amide hydrolase 1
  • Hepatic Lipase (HL)
  • LDL-associated phospholipase A2
  • Lipoprotein lipase
  • Monoacylglycerol lipase ABHD12
  • Monoacylglycerol lipase ABHD6
  • Multidrug resistance-associated protein 4
  • Neutral cholesterol ester hydrolase 1
  • Nuclear receptor subfamily 1 group I member 2
  • Pancreatic lipase
  • Pancreatic triacylglycerol lipase
  • Proteasome Macropain subunit
  • Proteasome component C5
  • Proteasome subunit beta type-1/beta type-5
  • Protein BAT5
  • Sn1-specific diacylglycerol lipase alpha
  • Sn1-specific diacylglycerol lipase beta
  • (2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl (2S)-2-formamido-4-methylpentanoate
  • CHEMBL175247
  • Orlistat
  • THLP
  • Tetrahydrolipstatin
  • US9328123, Orlistat
  • Xenical
27 Ki 33 IC50 4 EC50
  • Delta-type opioid receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Opioid receptors; mu & delta
  • (S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid
  • 3-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid
  • CHEMBL317956
  • DELTORPHIN C
  • H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2
  • deltorphin C
62 IC50 2 EC50
  • 5-Lipoxygenase/5-lipoxygenase activating protein
  • 5-lipoxygenase/FLAP
  • Arachidonate 5-lipoxygenase
  • Cyclooxygenase
  • Macrophage-expressed gene 1 protein
  • Prostaglandin E synthase
  • Prostaglandin E synthase 2
  • Prostaglandin G/H synthase (cyclooxygenase)
  • Replicase polyprotein 1ab
  • streptokinase A precursor
  • 3-(1-(4-chlorobenzyl)-3-(tert-butylthio)-5-isopropyl-1H-indol-2-yl)-2,2-dimethylpropanoic acid
  • 3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-isopropyl-1H-indol-2-yl)-2,2-dimethylpropanoic acid
  • 3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid
  • 3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-isopropyl-1H-indol-2-yl]-2,2-dimethyl-propionic acid
  • CHEMBL29097
  • MK-886
  • MK886
  • cid_3651377
52 Ki 7 IC50 1 Kd 4 EC50
  • 5-hydroxytryptamine receptor 1A
  • Adrenergic receptor alpha-2
  • Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Serotonin (5-HT) receptor
  • Sigma non-opioid intracellular receptor 1
  • (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol
  • (+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin
  • (R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol
  • 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol
  • 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol
  • 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)
  • 7-OH-DPAT
  • 7-OH-DPAT,(+)
  • 7-OH-DPAT,(-)
  • 7-hydroxy-2-(dipropylamino)tetralin
  • CHEMBL1255966
  • CHEMBL285755
3 Ki 22 IC50 39 EC50
  • Melanocortin receptor (M1 and M4)
  • Melanocortin receptor (M3 and M4)
  • Melanocortin receptor (M4 and M5)
  • Melanocortin receptor 1
  • Melanocortin receptor 3
  • Melanocortin receptor 4
  • Melanocortin receptor 5 (MC5R)
  • Melanocyte-stimulating hormone receptor
  • MELATONAN
  • Melatonan
53 Ki 11 IC50
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • Alpha-1A adrenergic receptor
  • Beta-2 adrenergic receptor
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cytochrome P450 1A2
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • HTR2C
  • Histamine H1 receptor
  • Multidrug resistance-associated protein 4
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Norepinephrine Monoamine transporters
  • Norepinephrine transporter
  • Potassium voltage-gated channel subfamily H member 2
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sigma non-opioid intracellular receptor 1
  • Sodium channel protein type 5 subunit alpha
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
  • Voltage-dependent L-type calcium channel subunit alpha-1C
  • adrenergic Alpha2
  • (1E)-5-methoxy-1-[4-(trifluoromethyl)phenyl]pentan-1-one O-(2-aminoethyl)oxime
  • CHEMBL814
  • FLUVOXAMINE
60 Ki 4 EC50
  • 5-HT3A Serotonin Receptor
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 3A
  • 5-hydroxytryptamine receptor 4 (5-HT4)
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • BDKRB2
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • Beta-3 adrenergic receptor
  • CCKBR
  • Calcium channel
  • Cholecystokinin receptor
  • Cholinergic, muscarinic
  • Cysteinyl leukotriene receptor 1
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Delta-type opioid receptor
  • GRIA3
  • Glutamate receptor ionotropic, NMDA 1
  • Glycine transporter 1
  • Glycine transporter 2
  • Histamine H1 receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M2
  • NT
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neuromedin-K receptor
  • Norepinephrine transporter
  • Prostanoid TP receptor
  • Serotonin (5-HT) receptor
  • Sigma-1
  • Sodium-dependent dopamine transporter
  • VIPR1
  • Voltage-gated sodium channel subunit alpha Nav1.8
  • 4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxylic acid [1-(3-methoxy-propyl)-piperidin-4-yl]-amide
  • CHEMBL117287
  • PRUCALOPRIDE
  • US9663465, prucalopride
64 IC50
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 3A
  • Adenosine receptor A2a
  • Adenosine receptor A3
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Amine oxidase (flavin-containing) A
  • Androgen Receptor
  • Angiotensin II receptor
  • BDKRB2
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • Beta-3 adrenergic receptor
  • Bradykinin B1 receptor
  • Cannabinoid receptor 1
  • Cholecystokinin receptor
  • Corticotropin releasing factor receptor 1
  • Corticotropin releasing factor receptor 2
  • Cyclooxygenase
  • Cyclooxygenase-1 (COX-1)
  • Cytochrome P450 2C9
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • Delta-type opioid receptor
  • Dopamine receptor D2L/neurotensin receptor NTS1
  • EDNRB
  • Endothelin-1 receptor
  • Estradiol receptor beta (ERβ)
  • Estrogen receptor
  • Gastric inhibitory polypeptide receptor
  • Ghrelin receptor
  • Glucagon receptor
  • Glucocorticoid receptor
  • Histamine H1 receptor
  • Histamine H2 Receptor
  • Histamine H3 receptor
  • Hydroxycarboxylic acid receptor 2
  • Kappa-type opioid receptor
  • Melanocortin receptor 3
  • Melanocortin receptor 4
  • Motilin receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Neurokinin 1 receptor
  • Neuropeptide Y receptor type 1
  • Neuropeptide Y receptor type 2
  • Potassium voltage-gated channel subfamily H member 2
  • Prostanoid TP receptor
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
  • Vasopressin V1a receptor
  • Vasopressin V2 receptor
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D
  • (1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-tetrahydrospiro-[beta-carboline-1,3'-indol]-2'(1'H)-one
  • CHEMBL1082723
  • NITD609
64 IC50
  • Dual specificity phosphatase Cdc25B
  • Protein tyrosine phosphatase 1B (PTP1B)
  • Protein-tyrosine phosphatase 1B
  • Protein-tyrosine phosphatase 1C
  • Receptor-type tyrosine-protein phosphatase F (LAR)
  • Receptor-type tyrosine-protein phosphatase S
  • T-cell protein-tyrosine phosphatase
  • Tyrosine-protein phosphatase non-receptor type 11
  • Tyrosine-protein phosphatase non-receptor type 2
  • Tyrosyl-DNA phosphodiesterase 1
  • Tyrosyl-DNA phosphodiesterase 2
  • CHEMBL179166
  • Sodium orthovanadate (SOV)
  • Vanadates
64 Ki
  • SSTR1
  • SSTR2
  • SSTR3
  • SSTR4
  • SSTR5
  • Somatostatin receptor type 1
  • Somatostatin receptor type 2
  • Somatostatin receptor type 3
  • Somatostatin receptor type 4
  • Somatostatin receptor type 5
  • BIM 23056
64 Ki
  • 5-HT3A Serotonin Receptor
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 7 (5HT7)
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • CCKBR
  • Calcium channel
  • Cholecystokinin B
  • Cholinergic, muscarinic
  • Cysteinyl leukotriene receptor 1
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Delta-type opioid receptor
  • Gamma-aminobutyric acid receptor subunit alpha-1
  • HTR1D
  • HTR2C
  • Histamine H1 receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M2
  • NT
  • Norepinephrine transporter
  • Prostanoid TP receptor
  • Serotonin (5-HT) receptor
  • Serotonin 1B/1D receptor
  • Sigma non-opioid intracellular receptor 1
  • Sodium-dependent dopamine transporter
  • Sodium-dependent serotonin transporter
  • Substance P
  • Voltage-gated sodium channel subunit alpha Nav1.8
  • adrenergic Alpha2
  • CAS_163091
  • NSC_163091
  • ORG-5222