27 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Discovery and characterization of novel CYP1B1 inhibitors based on heterocyclic chalcones: Overcoming cisplatin resistance in CYP1B1-overexpressing lines.
De Montfort University
Targeting cytochrome P450 (CYP) 1B1 with steroid derivatives.
Chu De Qu£Bec - Research Center (Chul)
A Ligand-Based Drug Design. Discovery of 4-Trifluoromethyl-7,8-pyranocoumarin as a Selective Inhibitor of Human Cytochrome P450 1A2.
Xavier University Of Louisiana
Design and Synthesis of Newa-Naphthoflavones as Cytochrome P450 (CYP) 1B1 Inhibitors To Overcome Docetaxel-Resistance Associated with CYP1B1 Overexpression.
Shanghai Jiao Tong University
Design, synthesis and evaluation of the inhibitory selectivity of novel trans-resveratrol analogues on human recombinant CYP1A1, CYP1A2 and CYP1B1.
Poznan University Of Medical Sciences
Targeting cytochrome P450 enzymes: a new approach in anti-cancer drug development.
University Of Maryland
Effect of structural modification on the inhibitory selectivity of rutaecarpine derivatives on human CYP1A1, CYP1A2, and CYP1B1.
National Research Institute Of Chinese Medicine
Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids.
University Of Crete
Selective inhibition of methoxyflavonoids on human CYP1B1 activity.
University Of Shizuoka
Design, synthesis, and discovery of novel trans-stilbene analogues as potent and selective human cytochrome P450 1B1 inhibitors.
Seoul National University
Cink4T, a quinazolinone-based dual inhibitor of Cdk4 and tubulin polymerization, identified via ligand-based virtual screening, for efficient anticancer therapy.
De Montfort University
Strategies for the development of highly selective cytochrome P450 inhibitors: Several CYP targets in current research.
Shenyang Pharmaceutical University
Synthesis and structure-activity relationship studies of ?-naphthoflavone derivatives as CYP1B1 inhibitors.
Shanghai Jiao Tong University
Discovery of new indole-based acylsulfonamide Na
Bristol-Myers Squibb Research And Development
Phytoestrogens and their synthetic analogues as substrate mimic inhibitors of CYP1B1.
Birla Institute Of Technology
Adaptable Small Ligand of CYP1 Enzymes for Use in Understanding the Structural Features Determining Isoform Selectivity.
Seoul National University
Design and synthesis of selective CYP1B1 inhibitor via dearomatization of ?-naphthoflavone.
Showa Pharmaceutical University
Targeting Cytochrome P450 (CYP) 1B1 Enzyme with Four Series of A-Ring Substituted Estrane Derivatives: Design, Synthesis, Inhibitory Activity, and Selectivity.
Chu De Qu£Bec-Research Center
Glycyrrhiza glabra extract and quercetin reverses cisplatin resistance in triple-negative MDA-MB-468 breast cancer cells via inhibition of cytochrome P450 1B1 enzyme.
Csir-Indian Institute Of Integrative Medicine
(E)-3-(3,4,5-Trimethoxyphenyl)-1-(pyridin-4-yl)prop-2-en-1-one, a heterocyclic chalcone is a potent and selective CYP1A1 inhibitor and cancer chemopreventive agent.
De Montfort University
Structure-Based Design and Synthesis of New Estrane-Pyridine Derivatives as Cytochrome P450 (CYP) 1B1 Inhibitors.
Chu De Qu£Bec-Research Center
Synthesis and biological evaluation of pyrrole-based chalcones as CYP1 enzyme inhibitors, for possible prevention of cancer and overcoming cisplatin resistance.
De Montfort University