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Found 13 of affinity data for UniProtKB/TrEMBL: A0A1G4H0K4
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. vivax)
The Board of Regents of The University of Texas System

US Patent
LigandPNGBDBM50567964(CHEMBL4858336 | US11903936, Compound 29)
Affinity DataIC50:  12nMAssay Description:The 50% inhibitory concentration (IC50) for the described compounds was determined using the 2,6-dichloroindophenol (DCIP) assay to monitor the DHODH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. vivax)
The Board of Regents of The University of Texas System

US Patent
LigandPNGBDBM50567990(CHEMBL4846297 | US11903936, Compound 8)
Affinity DataIC50:  32nMAssay Description:The 50% inhibitory concentration (IC50) for the described compounds was determined using the 2,6-dichloroindophenol (DCIP) assay to monitor the DHODH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. vivax)
The Board of Regents of The University of Texas System

US Patent
LigandPNGBDBM50567992(CHEMBL4846204 | US11903936, Compound 11)
Affinity DataIC50:  41nMAssay Description:The 50% inhibitory concentration (IC50) for the described compounds was determined using the 2,6-dichloroindophenol (DCIP) assay to monitor the DHODH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. vivax)
The Board of Regents of The University of Texas System

US Patent
LigandPNGBDBM50567995(CHEMBL4851471 | US11903936, Compound 20)
Affinity DataIC50:  41nMAssay Description:The 50% inhibitory concentration (IC50) for the described compounds was determined using the 2,6-dichloroindophenol (DCIP) assay to monitor the DHODH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. vivax)
The Board of Regents of The University of Texas System

US Patent
LigandPNGBDBM50567967(CHEMBL4850393 | US11903936, Compound 35)
Affinity DataIC50:  41nMAssay Description:The 50% inhibitory concentration (IC50) for the described compounds was determined using the 2,6-dichloroindophenol (DCIP) assay to monitor the DHODH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. vivax)
The Board of Regents of The University of Texas System

US Patent
LigandPNGBDBM50567994(CHEMBL4864218 | US11903936, Compound 17)
Affinity DataIC50:  43nMAssay Description:The 50% inhibitory concentration (IC50) for the described compounds was determined using the 2,6-dichloroindophenol (DCIP) assay to monitor the DHODH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. vivax)
The Board of Regents of The University of Texas System

US Patent
LigandPNGBDBM651975(3-methyl-N-(1-(1H-pyrazol-4-yl)ethyl)-4-(((trifluo...)
Affinity DataIC50:  43nMAssay Description:The 50% inhibitory concentration (IC50) for the described compounds was determined using the 2,6-dichloroindophenol (DCIP) assay to monitor the DHODH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. vivax)
The Board of Regents of The University of Texas System

US Patent
LigandPNGBDBM50567991(CHEMBL4848632 | US11903936, Compound 2)
Affinity DataIC50:  52nMAssay Description:The 50% inhibitory concentration (IC50) for the described compounds was determined using the 2,6-dichloroindophenol (DCIP) assay to monitor the DHODH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. vivax)
The Board of Regents of The University of Texas System

US Patent
LigandPNGBDBM651960(N-(1-(1H-1,2,4-triazol-3-yl) ethyl)-4-(3-fluoro-4-...)
Affinity DataIC50:  61nMAssay Description:The 50% inhibitory concentration (IC50) for the described compounds was determined using the 2,6-dichloroindophenol (DCIP) assay to monitor the DHODH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. vivax)
The Board of Regents of The University of Texas System

US Patent
LigandPNGBDBM50365230(CHEMBL1956285 | US11903936, Compound DSM265 | US92...)
Affinity DataIC50:  72nMAssay Description:The 50% inhibitory concentration (IC50) for the described compounds was determined using the 2,6-dichloroindophenol (DCIP) assay to monitor the DHODH...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. vivax)
The Board of Regents of The University of Texas System

US Patent
LigandPNGBDBM50567998(CHEMBL4876457 | US11903936, Compound 26)
Affinity DataIC50:  74nMAssay Description:The 50% inhibitory concentration (IC50) for the described compounds was determined using the 2,6-dichloroindophenol (DCIP) assay to monitor the DHODH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. vivax)
The Board of Regents of The University of Texas System

US Patent
LigandPNGBDBM651971(3-((1-(3-methyl-4-(1-(6-(trifluoromethyl)pyridin-3...)
Affinity DataIC50:  170nMAssay Description:The 50% inhibitory concentration (IC50) for the described compounds was determined using the 2,6-dichloroindophenol (DCIP) assay to monitor the DHODH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. vivax)
The Board of Regents of The University of Texas System

US Patent
LigandPNGBDBM651979(US11903936, Compound 25)
Affinity DataIC50:  260nMAssay Description:The 50% inhibitory concentration (IC50) for the described compounds was determined using the 2,6-dichloroindophenol (DCIP) assay to monitor the DHODH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent