BDBM13425 (15S)-5-hydroxy-4-methoxy-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-trien-14-yl sulfamate::oestrogen deriv. 10

SMILES COc1cc2C3CC[C@]4(C)C(CCC4C3CCc2cc1O)OS(N)(=O)=O

InChI Key InChIKey=AOEHUXLJSHGXHN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13425   

TargetCarbonic anhydrase 2(Human)
St. Mary'S Hospital

LigandPNGBDBM13425((15S)-5-hydroxy-4-methoxy-15-methyltetracyclo[8.7....)
Affinity DataIC50: 526nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
St. Mary'S Hospital

LigandPNGBDBM13425((15S)-5-hydroxy-4-methoxy-15-methyltetracyclo[8.7....)
Affinity DataIC50: 1.00E+4nMAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed