BDBM217081 US9302989, 375

SMILES O=C(Nc1ccc(cc1)-c1cncc2ccccc12)N1Cc2ccccc2C1

InChI Key InChIKey=QVRNDEAQJUMQKU-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 217081   

TargetNicotinamide phosphoribosyltransferase(Human)
Abbvie

US Patent
LigandPNGBDBM217081(US9302989, 375)
Affinity DataIC50: 595nMpH: 7.5Assay Description:Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2017
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Abbvie

US Patent
LigandPNGBDBM217081(US9302989, 375)
Affinity DataKi:  4.06E+3nMAssay Description:HTRF assay: This assay used the CisBio HTRF KinEASE kit (kit 62ST2PEZ) and the kinase reaction containing 0.2 uM biotinylated substrate peptide (S2, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2017
Entry Details
US Patent