BDBM26586 4-{5-[(3Z)-1-(carboxymethyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl}butanoic acid::H1-A1NI2, 11

SMILES OC(=O)CCCN1C(=S)S\C(C1=O)=C1/C(=O)N(CC(O)=O)c2ccccc12

InChI Key InChIKey=DDHULUGLYLPFHQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26586   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandPNGBDBM26586(4-{5-[(3Z)-1-(carboxymethyl)-2-oxo-2,3-dihydro-1H-...)
Affinity DataIC50: 1.20E+4nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed