BDBM313290 N-(6-methyl-5-(3- (oxetan-3- yl)phenyl)pyridin-2-yl)- 3-(trifluoromethyl)- benzamide::US10167279, Example 22::US10167279, Example 24

SMILES Cc1ncc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cccc(c1)C1COC1

InChI Key InChIKey=FXNXFVFPIIFJDM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 313290   

LigandPNGBDBM313290(N-(6-methyl-5-(3- (oxetan-3- yl)phenyl)pyridin-2-y...)
Affinity DataIC50: 455nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

LigandPNGBDBM313290(N-(6-methyl-5-(3- (oxetan-3- yl)phenyl)pyridin-2-y...)
Affinity DataIC50: 595nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

LigandPNGBDBM313290(N-(6-methyl-5-(3- (oxetan-3- yl)phenyl)pyridin-2-y...)
Affinity DataIC50: 3.52E+3nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

LigandPNGBDBM313290(N-(6-methyl-5-(3- (oxetan-3- yl)phenyl)pyridin-2-y...)
Affinity DataIC50: 3.76E+3nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent