BDBM50026581 CHEMBL103836

SMILES Cc1nn(-c2ccc(Cl)cc2)c2c1c(=O)oc1ccccc21

InChI Key InChIKey=MDCDQTYITMCZET-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50026581   

TargetCarbonic anhydrase 9(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50026581(CHEMBL103836)
Affinity DataKi:  403nMAssay Description:Inhibition of human CA9 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50026581(CHEMBL103836)
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGF2alpha formation incubated for 18 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50026581(CHEMBL103836)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human CA2 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50026581(CHEMBL103836)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human CA12 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50026581(CHEMBL103836)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human CA1 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50026581(CHEMBL103836)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGF2alpha formation incubated for 18 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed