BDBM50099119 5-Biphenyl-4-yl-5-ethyl-pyrimidine-2,4,6-trione::CHEMBL367524

SMILES CCC1(C(=O)NC(=O)NC1=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=XWZIZWWEAJZAMO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50099119   

TargetMatrix metalloproteinase-9(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099119(5-Biphenyl-4-yl-5-ethyl-pyrimidine-2,4,6-trione | ...)
Affinity DataIC50: 696nMAssay Description:Inhibition of Gelatinase B, matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099119(5-Biphenyl-4-yl-5-ethyl-pyrimidine-2,4,6-trione | ...)
Affinity DataIC50: 898nMAssay Description:Inhibition of Gelatinase A, matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099119(5-Biphenyl-4-yl-5-ethyl-pyrimidine-2,4,6-trione | ...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099119(5-Biphenyl-4-yl-5-ethyl-pyrimidine-2,4,6-trione | ...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of Stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099119(5-Biphenyl-4-yl-5-ethyl-pyrimidine-2,4,6-trione | ...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of matrilysin, Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed