BDBM50150575 1-Methyl-4-[4-(5-pyridin-2-yl-isoxazol-3-yl)-phenoxymethyl]-piperazine::CHEMBL183537

SMILES CN1CCN(COc2ccc(cc2)-c2cc(on2)-c2ccccn2)CC1

InChI Key InChIKey=OENAZTFZHICAGM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50150575   

TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150575(1-Methyl-4-[4-(5-pyridin-2-yl-isoxazol-3-yl)-pheno...)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed