BDBM50243125 CHEMBL487864::N3-(6-acetamidopyridin-3-yl)-4-methyl-N1-(3-(trifluoromethyl)phenyl)isophthalamide

SMILES CC(=O)Nc1ccc(NC(=O)c2cc(ccc2C)C(=O)Nc2cccc(c2)C(F)(F)F)cn1

InChI Key InChIKey=CRVJWQKUGJBXHH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243125   

LigandPNGBDBM50243125(N3-(6-acetamidopyridin-3-yl)-4-methyl-N1-(3-(trifl...)
Affinity DataIC50: 2nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50243125(N3-(6-acetamidopyridin-3-yl)-4-methyl-N1-(3-(trifl...)
Affinity DataIC50: 45nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50243125(N3-(6-acetamidopyridin-3-yl)-4-methyl-N1-(3-(trifl...)
Affinity DataIC50: 114nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed