BDBM5536 (3-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}phenyl)methanol::O6-Cyclohexylmethylguanine deriv. 20::[3-(6-Cyclohexylmethoxy-9H-purin-2-ylamino)phenyl]methanol

SMILES OCc1cccc(Nc2nc(OCC3CCCCC3)c3[nH]cnc3n2)c1

InChI Key InChIKey=ZRVXNDIHCVWDSH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5536   

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
University of Newcastle

LigandPNGBDBM5536((3-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}phe...)
Affinity DataIC50: 300nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2005
Entry Details Article
PubMed
TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2(Human)
University of Newcastle

LigandPNGBDBM5536((3-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}phe...)
Affinity DataIC50: 400nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2005
Entry Details Article
PubMed