BDBM7782 4-Benzyl-2-ethyl-1,2,4-thiadiazolidine-3,5-dione::CHEMBL26241::Thiadiazolidinone (TDZD) deriv. 9

SMILES CCn1sc(=O)n(Cc2ccccc2)c1=O

InChI Key InChIKey=VNCNRIGKOMHMLM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7782   

TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM7782(CHEMBL26241 | 4-Benzyl-2-ethyl-1,2,4-thiadiazolidi...)
Affinity DataIC50: 7.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM7782(CHEMBL26241 | 4-Benzyl-2-ethyl-1,2,4-thiadiazolidi...)
Affinity DataIC50: 7.15E+3nMAssay Description:Inhibition of GSK3-beta by Z'-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM7782(CHEMBL26241 | 4-Benzyl-2-ethyl-1,2,4-thiadiazolidi...)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed