BDBM102312 US8536193, 1-9

SMILES NC(=O)n1c2cc(-c3ccccc3)c(nc2ccc1=N)-c1ccc(cc1)C1(CCC1)NC(=O)Cc1cccnc1

InChI Key InChIKey=FMFQPADNNUZVJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 102312   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102312(US8536193, 1-9)
Affinity DataIC50: 39nMpH: 7.5Assay Description:Activated Akt isoforms and pleckstrin homology domain deletion constructs were assayed utilizing a GSK-derived biotinylated peptide substrate. The e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2013
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102312(US8536193, 1-9)
Affinity DataIC50: 200nMpH: 7.5Assay Description:Activated Akt isoforms and pleckstrin homology domain deletion constructs were assayed utilizing a GSK-derived biotinylated peptide substrate. The e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2013
Entry Details
US Patent