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BDBM103735 US10206907, Compound 141::US11000528, Cpd # 9::US8563545, 9
SMILES: CC(=O)N1CCN(Cc2ccc(cc2)-c2cccc3nc(NC(=O)C4CC4)nn23)CC1
InChI Key: InChIKey=XZLHQLMJMSXUMH-UHFFFAOYSA-N
Data: 5 IC50
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Tyrosine-protein kinase JAK1 [850-1154] (Human) | BDBM103735![]() (US8563545, 9 | US10206907, Compound 141 | US110005...) | GoogleScholar | UniChem | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK1 (Human) | BDBM103735![]() (US8563545, 9 | US10206907, Compound 141 | US110005...) | GoogleScholar | UniChem | n/a | n/a | 334 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK2 (Human) | BDBM103735![]() (US8563545, 9 | US10206907, Compound 141 | US110005...) | GoogleScholar | UniChem | n/a | n/a | 849 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK1 [850-1154] () | BDBM103735![]() (US8563545, 9 | US10206907, Compound 141 | US110005...) | GoogleScholar | UniChem | n/a | n/a | 334 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK2 [808-1132] (Human) | BDBM103735![]() (US8563545, 9 | US10206907, Compound 141 | US110005...) | GoogleScholar | UniChem | n/a | n/a | 849 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||