BDBM103737 US10206907, Compound 234::US11000528, Cpd # 11::US8563545, 11

SMILES: FC1(F)CCN(Cc2ccc(cc2)-c2cccc3nc(NC(=O)C4CC4)nn23)CC1

InChI Key: InChIKey=PFKFICBDHPHHLW-UHFFFAOYSA-N

Data: 14 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 103737   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 [850-1154] (Human)	BDBM103737 (US8563545, 11 | US10206907, Compound 234 | US11000...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [808-1132] (Human)	BDBM103737 (US8563545, 11 | US10206907, Compound 234 | US11000...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 [781-1124] (Human)	BDBM103737 (US8563545, 11 | US10206907, Compound 234 | US11000...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Human)	BDBM103737 (US8563545, 11 | US10206907, Compound 234 | US11000...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.69	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM103737 (US8563545, 11 | US10206907, Compound 234 | US11000...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM103737 (US8563545, 11 | US10206907, Compound 234 | US11000...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	195	n/a	n/a	n/a	n/a	n/a	n/a
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Non-receptor tyrosine-protein kinase TYK2 (Human)	BDBM103737 (US8563545, 11 | US10206907, Compound 234 | US11000...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 [850-1154] ()	BDBM103737 (US8563545, 11 | US10206907, Compound 234 | US11000...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.69	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [808-1132] (Human)	BDBM103737 (US8563545, 11 | US10206907, Compound 234 | US11000...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 [781-1124] (Human)	BDBM103737 (US8563545, 11 | US10206907, Compound 234 | US11000...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	195	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 [871-1187] (Human)	BDBM103737 (US8563545, 11 | US10206907, Compound 234 | US11000...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM103737 (US8563545, 11 | US10206907, Compound 234 | US11000...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Human)	BDBM103737 (US8563545, 11 | US10206907, Compound 234 | US11000...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Human)	BDBM103737 (US8563545, 11 | US10206907, Compound 234 | US11000...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair